About Us

John O

John O'Callaghan

Deputy Director

[email protected]

John is a graduate of King’s College London Medical School, where he intercalated a BSc before graduating as a doctor in 2006. He is currently a registrar in general surgery in Oxford, having become a member of the Royal College of Surgeons of England in 2009. John’s particular interest is organ preservation and he has published a number of reviews with the CET on this topic. He has recently completed his doctoral thesis entitled "Evidence based hypothermic preservation of the kidney and liver for transplantation" and will graduate from the University of Oxford in 2015.

John is currently in full-time surgical training but maintains strong links with the CET and has now taken on a role as deputy director. John has formal training in literature searching, critical appraisal, systematic review and surgical research methodology. He is a regular contributor to the Transplant Trial Watch and supervises junior research fellows.

Publications

O'Callaghan JM, Pall KT, Pengel L, Consortium for Organ preservation in Europe (COPE). Supplemental oxygen during hypothermic kidney preservation: A systematic review. Transplant Rev (Orlando) 2017 [Epub ahead of print] [PMID:28259374]

O'Donoghue KJM, Reed RD, Knight SR, O'Callaghan JM, Ayaz-Shah AA, Hassan S, Weißenbacher A, Morris PJM, Locke J, Pengel LHM. Critical appraisal of international clinical practice guidelines in kidney transplantation using the Appraisal of Guidelines for Research and Education (AGREE) II tool: A systematic review. 2017 (Accepted Abstract at the BTS Congress, Yorkshire, UK, 1-3 March, 2017).

O’Donoghue KJM, Reed RD, Knight SR, O’Callaghan JM, Ayaz-Shah AA, Hassan S, Morris PJ, Pengel LHM. Systematic review of clinical practice guidelines in kidney transplantation. BJS Open 2017; 1(4): 97–105.

O'Donoghue KJM, Deierhoi RJ, Knight SR, O'Callaghan JM, Morris PJ, Locke J, Pengel LHM. Critical Appraisal of Clinical Practice Guidelines in Kidney Transplantation using the Appraisal of Guidelines for Research and Education (AGREE) II tool: A Systematic Review. 2016. (Poster presentation at the BTS Congress, Glasgow, UK, 24-26 February, 2016).

Jochmans I, Akhtar MZ, Nasralla D, Kocabayoglu P, Boffa C, Kaisar M, Brat A, O'Callaghan J, Pengel LH, Knight S, Ploeg R. Past, present and future of dynamic kidney and liver preservation and resuscitation. Am J Transplant. 2016 [Epub ahdead of print] [PMID:26946212]

Hurst K, O'Callaghan J, Handa A. Risk impact of edoxaban in the management of stroke and venous thromboembolism [Accepted for publication]

Hotchen A, Coleman G, O’Callaghan J, McWhinnie D. Safe and Sustainable Increases in Day Case Emergency Surgery. British Journal of Hospital Medicine, Mar 2016; 77(3):180-183 [PMID:26961450]

O'Callaghan JM, Knight SR, Morgan RD, Morris PJ. A National Registry Analysis of Kidney Allografts Preserved With Marshall's Solution in the United Kingdom. Transplantation. 2016 Nov;100(11):2447-2452. [PMID:26760566]

Pengel LHM, Pall K, O'Callaghan J. Hypothermic Versus Normothermic In Situ Regional Perfusion Using The Extracorporeal Membrane Oxygenation (ECMO) Technique In Donation After Circulatory Death (DCD) In Kidney And Liver Transplantation: A Systematic Review [0216]. (Poster presentation at the joint BTS/NTV Congress, Bournemouth, UK, 11-13 March, 2015).

O'Callaghan JM, Morgan RD, Knight SR and Morris PJ. The Effect of Preservation Solutions for Storage of Liver Allografts on Transplant Outcomes: A Systematic Review and Meta-analysis. Annals of Surgery. 2014 Jul; 260(1):46-55 [PMID:24374537]

O'Callaghan J, Leuvenink H, Friend P, Ploeg R. Kidney Preservation, Chapter 9 in: Kidney Transplantation, Principles and Practice 7th Edition. Saunders. Eds Peter J Morris and Stuart J Knechtle. p130-141

O'Callaghan J, Coleman G, Hastings K, O'Hara R, McWhinnie D. Sustainable increases in day case emergency surgery, one component of an improved pathway for emergency surgery referrals. Journal of One Day Surgery. 2014; 24. Suppl 3: p17.

Pall K, Pengel L, O'Callaghan J. What is the evidence for oxygenated hypothermic preservation in kidney transplantation? A systematic Review. (Poster presentation at the World Transplant Congress, San Francisco, 2014)

O'Callaghan J, Knight S, Morgan R, Morris P. A national registry analysis of kidney allograft preservation with Marshall's Solution in the United Kingdom (Poster presentation at the World Transplant Congress, San Francisco, 2014)

D'Ugo S, O'Callaghan J, Spoletini G, Soonawalla Z, Reddy S, Silva M. Techniques of pancreatic reconstruction after pancreaticoduodenectomy: analysis of pancreatic fistula rate and severity, risk factors and impact of omental wrap. (Poster presentation at Digestive Disease Week, Chicago 2014)

O'Callaghan J, Coleman G, Hastings K, O'Hara R, McWhinnie D. Sustainable increases in day case emergency surgery, one component of an improved pathway for emergency surgery referrals. (Oral at the British Association of Day Surgery, Scarborough 2014)

O'Callaghan J, Knight S, Morgan R, Morris P. A national registry analysis of kidney allograft presentation with Marshall's Solution in the United Kingdom. (Oral at the British Transplantation Society, Glasgow 2014)

O'Callaghan JM, Morgan RD, Knight SR, Morris PJ. Systematic review and meta-analysis of hypothermic machine perfusion versus static cold storage for kidney allografts on transplant outcomes. British Journal of Surgery. 2013 Jul; 100(8):991-1001. [PMID:23754643]

O'Callaghan J, Morgan R, Knight S, Morris P. Systematic reviews of alemtuzumab in renal transplantation. Transplant Immunology. March 2013; 28 (2): 71. [PMID:23352935]

Pengel LHM, Knight S, Emin A, O’Callaghan J, Van der Meulen J, Papalois V, Morris PJ. How to teach evidence-based skills in 1.5 days: the Evidence in Transplantation (EVIT) Course. 16th Congress of the European Society for Organ Transplantation, September 8-11, 2013, Vienna, Austria

O'Callaghan J, Morgan R, Knight S, Morris P.Preservation solutions for static cold storage of liver allografts: A systematic review and meta-analysis. 16th Annual Congress of the British Transplantation Society, Bournemouth, 2013.

O'Callaghan J, Morgan R, Knight S, Morris P. Liver allograft preservation fluids: A systematic review and meta-analysis. Transplant International. 2013; 26(Supp s2):332

Pengel LHM, Knight S, Emin A, O'Callaghan J, Van der Meulen J, Papalois V, Morris P. How to teach evidence-based practice skills in 1.5 days: the Evidence in Transplantation (EVIT) course. Transplant International. 2013; 26(Supp s2);192

O'Callaghan J, Morgan R, Knight S, Morris P. Liver allograft preservation fluids: A Systematic review and Meta-Analysis. (Poster presentation at the European Society for Organ Transplantation, Vienna 2013)

Pengel L, Knight S, Emin A, O'Callaghan J, Van der Meulen J, Papalois V, Morris P. How to teach evidence-based practice skills in 1.5 days: The Evidence in Transplantation (EVIT) Course. (Poster presentation at the European Society for Organ Transplantation, Vienna 2013)

O'Callaghan JM, Knight SR, Morgan RD, Morris PJ. Preservation solutions for static cold storage of kidney allografts: a systematic review and meta-analysis. American Journal of Transplantation 2012; 12(4): 896-906. [PMID:22221739]

Morgan RD, O'Callaghan JM, Knight SR, Morris PJ. Alemtuzumab induction therapy in kidney transplantation: a systematic review and meta-analysis. Transplantation 2012; 93(12): 1179-1188 [PMID:22660659]

O’Callaghan J, Morgan R, Knight S, Morris P. Hypothermic machine preservation in comparison with static cold storage for kidney allografts. The Transplantation Society Congress, Berlin 2012

O’Callaghan J. Intestinal transplantation (Adrian Tanner Prize) Oral- Royal Society of Medicine, Surgery Section 2012

Morgan RD*, O’Callaghan JM, Knight SR, Morris PJ. Alemtuzumab induction therapy in kidney transplantation: a systematic review and meta-analysis. 24th International Congress of The Transplantation Society, Berlin, Germany. * presenting author

Morgan R, O'Callaghan J, Wagener S, Grant H, Lakhoo K. Surgical correction of trachea-oesophageal fistula and oesophageal atresia in VACTERL association: a retrospective case-control study. Paediatric Surgery International. Oct 2012; 28(10):967-970. [PMID:22991204]

Morgan R, O'Callaghan J, Knight S, Morris P. Alemtuzumab induction therapy in kidney transplantation: A Systematic Review and Meta-Analysis. Transplantation. 2012; 94(10S):972

O'Callaghan J. Hypothermic machine perfusion of kidneys. (Oral at the 16th National organ retrieval workshop, NHSBT, Oxford 2012)

O'Callaghan J. Evidence based use of organ preservation fluids. (Oral at the Royal College of Surgeons of England, NHSBT Organ Perfusion Protocol Meeting, London 2012)

O'Callaghan J. Intestinal transplantation (Adrian tanner prize). (Oral at the Royal Society of Medicine, Surgery Section 2012)

O'Callaghan J, Morgan R, Knight S, Morris P. Hypothermic machine preservation in comparison with static cold storage for kidney allografts: A Systematic review and Meta-Analysis. Transplantation. 2012; 94(10S):277

O’Callaghan J, Knight S, Morgan R, Morris P. Preservation solutions for static cold storage of kidney allografts. Oral- European Society of Organ Transplantation, Glasgow 2011

O’Callaghan J. Clinical trial evidence in transplantation: Nephrologist update Oral- Corpus Christi College, Oxford 2011

Sadideen H, O'Callaghan J, Navidi M, Sayegh M. Educating surgical patients to reduce the risk of venous thromboembolism: an audit of an effective strategy. Journal of the Royal Society of Medicine Short Reports. Dec 2011; 2(12):97. [PMID:22279607]

O'Callaghan J, Morgan R, Knight S, Morris P. Preservation solutions for static cold storage of kidney allografts: A Systematic Review and Meta-Analysis. Transplant International. 2011; 24(s2):204

O'Callaghan J, Sinha S, Quiroga Q, Perkins J, Darby C, Gilbert j. Steal Syndrome: Is there a role for branding? (Poster presentation at the Vascular Access Society of Britain and Ireland 2011)

O'Callaghan J, Pepper H, Pande R, Roberts K, Gilmour J. The impact of dedicated upper GI/HPB fellow upon emergency laparoscopic cholecystectomy. British Journal of Surgery. 2010; 97(s2):109

Roberts K, Gilmour J, Premaratne S, Pande R, O'Callaghan J. Efficacy of intraperitoneal local anaesthetic techniques at laparoscopic cholecystectomy: double blind randomized control trial. British Journal of Surgery. 2010; 97(s2):12

Roberts KJ, Gilmour J, Premaratne S, Pande R, O'Callaghan J. Novel analgesic technique during laparoscopic cholecystectomy decreases post-operative pain. (Oral presentation at the ASGBI Conference, Liverpool 2010)

O'Callaghan J, Roberts K, Gilmour J, Pande R, Pepper H, Cox N, Begum Z, Fraser I. The impact of a dedicated HPB/Upper GI fellow upon emergency laparoscopic cholecystectomy. (Poster presentation at ASGBI Conference, Liverpool 2010)

O'Callaghan J, Keh S, D'Souza A. Management of closed tracheal perforation following blunt trauma. Otalaryngology Head Neck Surgery. Nov 2009; 141(5):661-2 [PMID:19861212]

O'Callaghan J, Bewick J, Paice A, Ng P. Stabbing? Cause. BMJ Case Reports. 25 May 2009. [PMID:3286369]

O'Callaghan J, Carr R, Shah B, Marimuthu K, Mathew G. Do in-hospital delays increase perforation rates in acute appendicitis? Colorectal Disease. Sep 2009; 11(s2):36-37

O'Callaghan J, Carr R, Shah B, Marimuthu K, Mathew G. Non-patient factors and perforation rates in acute appendicitis. (Poster presentation at the European Society of Coloproctology, Prague 2009)

Bewick J, O'Callaghan J, Paice A, Ng P. How should stab wounds be managed? (Poster presentation at the ASIT Conference, Nottingham 2009)

Antonio M, Dada-Adegbola H, Biney E, Awine T, O'Callaghan J, Pfluger V, Enwere G, Okoko B, Oluwalana C, Vaughan A, Zaman S, Pluschke G, Greenwood BM, Cutts F, Adegbola RA. Molecular epidemiology of pneumococci obtained from Gambian children aged 2-29 months with invasive pneumococcal disease during a trial of a 9-valent pneumococcal conjugate vaccine. BMC Infectious Diseases. June 2008; 8:81 [PMID:18547404]

O'Callaghan J, Glore RJ, Hornigold R, D'Souza A. Thyroid chondroma as a differential for thyroglossal cyst. Otalaryngology Head Neck Surgery. Oct 2008; 139(4):594-595. [PMID:18922352]

O'Callaghan J, Keh S, D'Souza A. Management of closed tracheal perforation: A case report. (Poster presentation at the Joint Anglo-American ENT Meeting, Dublin 2008)

Bramis K, O'Callaghan J, Spoletini G, Friend P, Reddy S. Isolated liver perfusion for unresectable metastatic liver tumours: A systematic review. Surgical Science. (in press)

Starsung Collaborative Group (local lead). Impact of post-operative non-steroidal anti-inflammatory drugs on adverse events after gastrointestinal surgery. British Journal of Surgery (in press)

O'Callaghan J, Boyd J, Singh A. A stitch in time: an unusual case of enterovesical fistula. BMJ Case Reports (in press)