News

January 2017 Transplant Trial Watch now available

By: Simon Knight | Posted on 6th January 2017

The January 2017 edition of the Transplant Trial Watch is now available. This month, trials include risk of infection with RANKL inhibitors, kidney cooling during anastomosis and donor ischaemia preconditioning in liver transplantation.

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December 2016 Transplant Trial Watch now online

By: Simon Knight | Posted on 1st December 2016

The December 2016 edition of the Transplant Trial Watch is now available. This month, articles include a trial of fibrin glue to prevent complications after renal transplantation, a meta-analysis of renal outcomes in live kidney donors and the risk of biliary complications following live donor liver transplantation. It also includes an analysis of the HTA […]

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Coming Soon: The critical appraisal of Clinical Practice Guidelines in the Transplant Library

By: Katriona O'Donoghue | Posted on 21st November 2016

We have recently started adding Clinical Practice Guidelines (CPGs) published since 2005 on all aspects of solid organ transplantation to the Transplant Library database. These include consensus reports, documents and statements where specific recommendations or guidelines are given. In order to facilitate the easy identification of good quality CPGs we aim to appraise all newly […]

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Quality and consistency of outcome reporting in transplant clinical trials

By: Simon Knight | Posted on 3rd November 2016

Much focus is placed upon the methodological quality of clinical trials, and the impact that it has on the risk of bias at a study level.  An often neglected area is the reporting quality of the manuscripts from trials, which can also have a big impact on the interpretation of results. A recent paper in […]

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November 2016 Transplant Trial Watch is now available

By: Simon Knight | Posted on 1st November 2016

The November 2016 edition of the Transplant Trial Watch is now available on the CET website and via our app for iPhone, iPad and Android. This month, studies include a systematic review of fish oil for kidney transplant recipients, metal vs. plastic stents for benign biliary strictures, and cardiac transplantation after the Norwood procedure.

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Kidney Transplant PSP published in PLOS ONE

By: Simon Knight | Posted on 24th October 2016

The results of the Kidney Transplant Priority Setting Partnership have been published in PLOS ONE today. The journal is open access, so head to the PLOS ONE website now to get a copy. The project brought together clinicians, researchers, patients and carers to identify and prioritise areas for future research in kidney transplantation. You can read more […]

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October 2016 Transplant Trial Watch now available

By: Simon Knight | Posted on 3rd October 2016

The October 2016 edition of the Transplant Trial Watch is now online. This month includes a trial of Eculizumab for chronic antibody mediated rejection, a review of the impact of multiple renal arteries in renal transplantation and a trial of antibiotic treatment of ex-vivo perfused lungs.

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The explosion of systematic reviews – have we gone too far?

By: Simon Knight | Posted on 14th September 2016

A fascinating recent paper from Professor John Ioannidis from Stanford University, published in the Milbank Quarterly, has examined the explosion in the publication of systematic reviews and meta-analyses over recent years. Publications between 1991 and 2014 increased by 2,728% for systematic reviews, and 2,635% for meta-analyses – far in excess of the rate of publication […]

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September 2016 Transplant Trial Watch now available

By: Simon Knight | Posted on 5th September 2016

The September 2016 edition of the Transplant Trial Watch is now available. This month’s studies include include the perils of late CNI withdrawal, CNI to mTORi conversion in Liver Transplant recipients and computer-based home education.

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August 2016 Transplant Trial Watch now available

By: Simon Knight | Posted on 15th August 2016

The August 2016 edition of the Transplant Trial Watch is now available. This month’s edition includes systematic reviews of pre-emptive renal transplantation and management of ureteric strictures, along with trials of prostaglandin E1 in liver transplant recipients and C1 esterase inhibition in renal transplantation.

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