News

November 2017 Transplant Trial Watch now available

By: Simon Knight | Posted on 1st November 2017

The November 2017 Transplant Trial Watch is now available. This month’s papers include a non-inferiority study of low-dose sirolimus combined with tacrolimus in renal tranpslant recipients, a meta-anlysis of remote ischaemic conditioning protocols, and propofol to reduce hepatic ischaemia reperfusion injury.

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Management of asymptomatic bacteriuria after kidney transplantation – survey

By: Simon Knight | Posted on 6th July 2017

The ERA-EDTA DESCARTES working group have developed a short survey to collect information regarding current practice on the diagnosis and management of asymptomatic bacteriuria after adult kidney transplantation. This survey complements a clinical trial that they are running in this area. They would be very keen to hear from units in the UK so that […]

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July 2017 Transplant Trial Watch now online

By: Simon Knight | Posted on 5th July 2017

The July 2017 edition of the Transplant Trial Watch is now available. This month’s papers include a systematic review of factors affecting medication adherence following renal transplant, a trial of Belatacept versus tacrolimus in renal transplant recipients and a systematic review of transplant tourism.

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May 2017 Transplant Trial Watch now online

By: Simon Knight | Posted on 2nd May 2017

The May 2017 edition of the Transplant Trial watch is now out. This month’s studies include low dose valganciclovir prophylaxis in renal transplantation, metal vs. plastic stents for anastomotic strictures in liver transplantation and ex-vivo perfusion in cardiac transplantation.

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March 2017 Transplant Trial Watch now online

By: Simon Knight | Posted on 28th February 2017

The March 2017 edition of the Transplant Trial Watch is now available. This month’s papers include telemedicine for live donor follow-up, ACE inhibitors in renal transplant recipients and cancer screening recommendations following solid organ transplantation.

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June 2016 Transplant Trial Watch is now online

By: Simon Knight | Posted on 3rd June 2016

The June 2016 Transplant Trial Watch is now available. This month, the trial watch includes systematic reviews of quality of life reporting in renal transplant trials and extended criteria donors, as well as an analysis of wound complications with everolimus following cardiac transplantation.

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SONG-TX – developing a core outcome set for renal transplantation

By: Simon Knight | Posted on 17th February 2016

Many clinical trials have been conducted in kidney transplantation but a wide variety of different outcomes are reported and in different ways, and it is unclear whether they are important to people who have received a kidney transplant. There has been no agreement about what are the most important outcomes to measure and report in […]

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Help us to prioritise the most important questions in kidney transplantation

By: Simon Knight | Posted on 10th November 2015

The Centre for Evidence in Transplantation are currently leading a project to identify and prioritise unanswered research questions in kidney transplantation to help guide future research. The Kidney Transplant Priorities Setting Partnership has identified 45 unanswered questions, submitted by patients, clinicians, donors and carers. We are now trying to prioritise these questions to see which […]

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Join the discussion: recipient obesity and outcome after renal transplantation

By: Liset Pengel | Posted on 5th November 2015

Two recent systematic reviews were published on this important topic. The review by Lafranca and colleagues entitled “Body mass index and outcome in renal transplant recipients: a systematic review and meta-analysis”(BMC Medicine 2015;13(1):111) included 56 studies. The authors concluded that “Several of the pooled outcome measurements show significant benefits for ‘low’ BMI (30 preferably should […]

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Sirolimus associated with less malignancy but an increased mortality after kidney transplantation

By: Peter Morris | Posted on 6th January 2015

A group from Ottawa, led by Greg Knoll, have published an important systematic review of risk of cancer in patients who had sirolimus included with their immunosuppression de novo as well as those who were converted at some stage after transplantation to sirolimus. The study also included a meta-analysis of individual patient data. This was […]

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