Transplant Trial Watch

Randomized Controlled Trial of a Computer-Based Education Program in the Home for Solid Organ Transplant Recipients: Impact on Medication Knowledge, Satisfaction, and Adherence.

Harrison JJ, Badr S, et al.

Transplantation 2016 [record in progress].


Aims
To evaluate the impact of a home delivered computer-based education (CBE) program on medication knowledge, satisfaction and immunosuppressant adherence in de novo solid organ transplant recipients (SOTR).

Interventions
Participants were randomised to receive either the standard of care (control group), or the standard of care plus the Transplant Medication Information Teaching Tool (TMITT) as an online CBE program (intervention group).

Participants
246 SOTR.

Outcomes
The primary outcomes measured were change in knowledge and satisfaction. The secondary measured outcome was adherence to the immunosuppressive regimen.

Follow-up
3 months

CET Conclusions
De novo solid organ transplant recipients who had received standard, in-hospital, pharmacy-led self-medication teaching were randomised to receive additional computer-based education or no additional education. Power calculations showed that 110 patients per study arm were needed. The study randomised 246 patients using concealed allocation and 209 patients were included in the 3-month analysis. There were no differences between groups at 3 months in terms of medication knowledge, satisfaction with the medication information provided and medication adherence indicating that the computer-based education did not provide additional value to the standard, in-hospital self-medication programme alone.

Jadad score
3

Data analysis
Available case analysis

Allocation concealment
Yes

Trial registration
ClinicalTrials.gov Identifier - NCT01826721

Funding source
Industry funded