To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
October 2014
Kidney transplantation
Immunophenotyping and efficacy of low dose ATG in non-sensitized kidney recipients undergoing early steroid withdrawal: a randomized pilot study.
Grafals M, Smith B, Murakami N, et al. PLoS ONE. 2014; 9(8):e104408.
Understanding the relationship between trust in health care and attitudes toward living donor transplant among African Americans with end-stage renal disease.
McDonald EL, Powell CL, Perryman JP, et al. Clin Transplant. 2013; 27(4):619-26.
Comparison of barry and barry-taguchi ureterovesical reimplantation techniques in kidney transplantations: a randomized clinical trial.
Mohammadi Fallah M R, Taghizadeh Afshari A. International Journal of Organ Transplantation Medicine 2014; 1(2): 77-83.
Safety and efficacy of conversion from twice-daily tacrolimus to once-daily tacrolimus one month after transplantation: randomized controlled trial in adult renal transplantation.
Oh C K, Huh KH, et al. Yonsei Medical Journal 2014; 55(5): 1341-1347.
A randomized 2x2 factorial trial, part 1: single-dose rabbit antithymocyte globulin induction may improve renal transplantation outcomes.
Stevens RB, Foster KW, Miles CD, et al. Transplantation [record in progress].
Liver transplantation
Utility of a monitoring strategy for human herpes viruses 6 and 7 viremia after liver transplantation: a randomized clinical trial.
Fernandez-Ruiz M, Kumar D, Husain S, et al. Transplantation [record in progress].
Heart transplantation
Effect of high-intensity training versus moderate training on peak oxygen uptake and chronotropic response in heart transplant recipients: a randomized crossover trial.
Dall CH, Snoer M, Christensen S, et al. American journal of transplantation 2014; 14(10):2391-9
Lung transplantation
Intravenous immunoglobulin for hypogammaglobulinemia after lung transplantation: a randomized crossover trial.
Lederer DJ, Philip N, Rybak D, et al. PLoS ONE. 2014 ;9(8):e103908
Various organs
5-year results of a prospective, randomized, single-center study of alemtuzumab compared with rabbit antithymocyte globulin induction in simultaneous kidney-pancreas transplantation.
Stratta RJ, Rogers J, Orlando G, et al. Transplant Proc. 2014; 46(6):1928-31.
Combination of ablative fractional laser and daylight mediated photodynamic therapy for actinic keratosis in organ transplant recipients - a randomized controlled trial.
Togsverd-Bo K, Lei U, et al. British Journal of Dermatology [record in progress].