To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
January 2015
Kidney transplantation
The effect of bright light therapy on sleep and circadian rhythms in renal transplant recipients: a pilot randomized, multicentre wait-list controlled trial.
Burkhalter H, Wirz-Justice A, et al. Transplant international 2015; 28(1): 59-70
Randomized trial of three induction antibodies in kidney transplantation: Long-term results.
Ciancio G, Gaynor JJ, Guerra G, et al. Transplantation 2014; 97(11): 1128.
Beneficial effect of Belatacept on health-related quality of life and perceived side effects: results from the BENEFIT and BENEFIT-EXT trials.
Dobbels F, Wong S, Min Y, Sam J, et al. Transplantation 2014; 98: 960.
Cellular and molecular immune profiles in renal transplant recipients after conversion from tacrolimus to sirolimus.
Gallon L, Traitanon O, Sustento-Reodica N, et al. Kidney International. 2015 Apr; 87(4): 828-38
Accuracy of dialysis medical records in determining patients' interest in and suitability for transplantation.
Huml AM, Sullivan CM, Pencak JA, Sehgal AR. Clin Transplant 2013; 27(4):541-5.
An acetate-buffered balanced crystalloid versus 0.9% saline in patients with end-stage renal disease undergoing cadaveric renal transplantation: A prospective randomized controlled trial.
Potura E, Lindner G, Biesenbach P, et al. Anesthesia and Analgesia. 2015 Jan; 120(1): 123-9
Liver transplantation
Is minimal, [almost] steroid-free immunosuppression a safe approach in adult liver transplantation? Long-term outcome of a prospective, double blind, placebo-controlled, randomized, investigator-driven study.
Lerut JP, Pinheiro RS, Lai Q, et al. Ann Surg. 2014; 260:886.
Randomized, double-blind trial of Anidulafungin versus Fluconazole for prophylaxis of invasive fungal infections in high-risk liver transplant recipients.
Winston DJ, Limaye AP, Pelletier S, et al. American journal of transplantation 2014;14:2758
Heart transplantation
Myocyte growth, repair, and oxidative stress following pediatric heart transplantation.
Dipchand AI, White M, Manlhiot C, Pollock-BarZiv S, et al. Pediatric transplantation 2014; 18(7): 764-770.
Other
ABO antibody and complement depletion by immunoadsorption combined with membrane filtration - A randomized, controlled, cross-over trial.
Eskandary F, Wahrmann M, Biesenbach P, et al. Nephrology Dialysis Transplantation 2014; 29(3):706.