To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
October 2015
Kidney transplantation
Dyslipidaemia among renal transplant recipients: cyclosporine versus tacrolimus.
Fazal MA, Idrees MK, et al The Journal of the Pakistan Medical Association 2014;64(5):496-9
Eight-year results of the Spiesser study, a randomized trial comparing de novo sirolimus and cyclosporine in renal transplantation.
Gatault P, Bertrand D, et al. Transplant International 2015 [record in progress]
Aerobic or Resistance Training and Pulse Wave Velocity in Kidney Transplant Recipients: A 12-Week Pilot Randomized Controlled Trial (the Exercise in Renal Transplant [ExeRT] Trial).
Greenwood SA, Koufaki P, et al. American Journal Kidney Diseases 2015 Oct;66(4):689-98
Sirolimus vs cyclosporine after induction with basiliximab does not promote regulatory t cell expansion in de novo kidney transplantation: Results from a single-center randomized trial.
Libetta C, Esposito P, et al. Transplant Immunology 2015 Oct;33(2):117-24
A Double Blind Randomized Clinical Trial of Remote Ischemic Conditioning in Live Donor Renal Transplantation.
Nicholson ML, Pattenden CJ, et al. Medicine (Baltimore) 2015; 94(31): e1316
Therapeutic Hypothermia in Deceased Organ Donors and Kidney-Graft Function.
Niemann CU, Feiner J, et al. New England Journal of Medicine 2015; 373(5): 405-414.
Late Conversion of Kidney Transplant Recipients from Ciclosporin to Tacrolimus Improves Graft Function: Results from a Randomized Controlled Trial.
Plischke M, Riegersperger M, et al. PLoS ONE 2015; 10(8): e0135674.
A New HC-A II Solution for Kidney Preservation: A Multi-Center Randomized Controlled Trial in China.
Sui M, Zhang L, et al. Annals of Transplantation 2014; 19: 614-620.
Liver transplantation
Effects of two different techniques of postoperative analgesia management in liver transplant donors: a prospective, randomized, double-blind study.
Aydogan MS, Bicakcioglu M, et al. Transplantation Proceedings 2015; 47(4): 1204-1206.
Sustained Virological Response to Antiviral Therapy in a Randomized Trial of Cyclosporine versus Tacrolimus in Liver Transplant Patients with Recurrent Hepatitis C Infection.
Duvoux C, Villamil F, et al. Annals of Transplantation 2015; 20: 25-35.