To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
November 2015
Kidney transplantation
Risk factors associated with efficacy outcomes in kidney transplantation: analysis of a contemporary cohort of patients from the A2309 trial.
Colussi G, Vergara M, et al. Clinical Nephrology 2015 Jun; 83(6): 338-44.
Randomized Controlled Trial of Adjuvanted Versus Nonadjuvanted Influenza Vaccine in Kidney Transplant Recipients.
Kumar D, Campbell P, et al. Transplantation 2015 [record in progress].
Long-term safety and efficacy of antithymocyte globulin induction: use of integrated national registry data to achieve ten-year follow-up of 10-10 Study participants.
Lentine KL, Schnitzler MA, et al. Trials 2015; 16(1): 365.
Impact of sympathetic renal denervation: a randomized study in patients after renal transplantation (ISAR-denerve).
Schneider S, Promny D, et al. Nephrol Dial Transplant 2015 Nov; 30(11): 1928-36
Minilaparoscopy vs. standard laparoscopic donor nephrectomy: comparison of safety, efficacy and cosmetic outcomes in a randomized clinical trial.
Simforoosh N, HosseiniSharifi SH, et al. Urology Journal 2015; 12(4): 2223-2227.
CD25 blockade in kidney transplant patients randomized to standard-dose or high-dose basiliximab with cyclosporine, or high-dose basiliximab in a calcineurin inhibitor-free regimen.
Thibault G, Paintaud G, et al. Transplant International 2015 [record in progress]
Liver transplantation
Ledipasvir and Sofosbuvir Plus Ribavirin for Treatment of HCV Infection in Patients With Advanced Liver Disease.
Charlton M, Everson GT, et al. Gastroenterology 2015; 149(3): 649-659.
The Conversion of Once-daily Extended-release Tacrolimus is Safe in Stable Liver Transplant Recipients: A Randomized Prospective Study.
Kim JM, Kwon CH, et al. Liver Transpl 2015 [record in progress]
Sevoflurane Versus Desflurane on the Incidence of Postreperfusion Syndrome During Living Donor Liver Transplantation: A Randomized Controlled Trial.
Lee J, Yoo YJ, et al. Transplantation 2015 [record in progress]
Performance Characteristics of Galactomannan and beta-d-Glucan in High-Risk Liver Transplant Recipients.
Singh N, Winston DJ, et al. Transplantation 2015 [record in progress]