Transplant Trial Watch

To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.

The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].

The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.

Click on each trial for more detail of findings and quality.


December 2015

Kidney transplantation

Co-administration of sirolimus alters tacrolimus pharmacokinetics in a dose-dependent manner in adult renal transplant recipients.
Baldan N, Rigotti P, et al. Pharmacological Research 2006; 54(3): 181-185.

Robotic assisted laparoscopic donor nephrectomy versus standard laparoscopic donor nephrectomy: A prospective randomised comparative study.
Bhattu AS, Ganpule A, et al. J Endourol 2015 [record in progress].

Behavioral measures to reduce non-adherence in renal transplant recipients: a prospective randomized controlled trial.
Garcia MF, Bravin AM, et al. Int Urol Nephrol 2015; 47(11):1899-90

A Culturally Targeted Website for Hispanics/Latinos About Living Kidney Donation and Transplantation: A Randomized Controlled Trial of Increased Knowledge.
Gordon EJ, Feinglass J, et al. Transplantation 2015 [record in progess].

Ultrasound/Laparoscopic Camera-Guided Transversus Abdominis Plane Block for Renal Transplant Donors: A Randomized Controlled Trial.
Guner Can M, Goz R, et al. Annals of Transplantation 2015; 20: 418-423

Enhancing Kidney Function with Thrombolytic Therapy following Donation after Cardiac Death: A Multicenter Quasi-Blinded Prospective Randomized Trial.
Woodside KJ, Goldfarb DA, et al. Clinical Transplantation 2015 [record in progess].

Liver transplantation

Effect of stroke volume variation-directed fluid management on blood loss during living-donor right hepatectomy: a randomised controlled study.
Choi SS, Jun IG, et al. Anaesthesia 2015 [record in progress].

Blood glucose regulation during living-donor liver transplant surgery.
Gedik E, et al. Experimental & Clinical Transplantation 2015; 13 Suppl 1: 294-300

A new formula for calculating standard liver volume for living donor liver transplantation without using body weight.
Kokudo T, Hasegawa K, et al. Journal of Hepatology 2015; 63(4): 848-854.

Belatacept treatment for two yr after liver transplantation is not associated with operational tolerance.
Schwarz C, Rasoul-Rockenschaub S, et al. Clinical Transplantation 2015; 29(1): 85-89.