To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
October 2017
Kidney transplantation
Early low-dose erythropoiesis-stimulating agent therapy and progression of moderate chronic kidney disease: a randomized, placebo-controlled trial.
Fliser D, Dellanna D, et al. Nephrology Dialysis Transplantation 2017; 32(2): 279-287.
Protective Effects of L-Carnitine Against Delayed Graft Function in Kidney Transplant Recipients: A Pilot, Randomized, Double-Blinded, Placebo-Controlled Clinical Trial.
Jafari A, Khatami M-R, et al. Journal of Renal Nutrition 2017; 27(2): 113-126.
Can intraperitoneal bupivacaine decreases pain in patients undergoing laparoscopic live donor nephrectomy? A randomized control trial.
Jairath A, Ganpule A, et al. World Journal of Urology 2017; 35(6): 985-989.
Impact of Hyperuricemia on Long-term Outcomes of Kidney Transplantation: Analysis of the FAVORIT Study.
Kalil RS, Carpenter MA, et al. American Journal of Kidney Diseases 2017; 09: 09.
Calcineurin inhibitor withdrawal or tapering for kidney transplant recipients.
Karpe KM, Talaulikar GS, et al. Cochrane Database of Systematic Reviews 2017; 7: CD006750.
Design and approach of the Living Organ Video Educated Donors (LOVED) program to promote living kidney donation in African Americans.
Sieverdes JC, Price M, et al. Contemporary Clinical Trials 2017; 04: 04.
Ten-Year Outcomes in a Randomized Phase II Study of Kidney Transplant Recipients Administered Belatacept 4-Weekly or 8-Weekly.
Vincenti F, Blancho G, et al. American Journal of Transplantation 2017; 31: 31.
Polyclonal and monoclonal antibodies for treating acute rejection episodes in kidney transplant recipients.
Webster AC, Wu S, et al. Cochrane Database of Systematic Reviews 2017; 7: CD004756.
Liver transplantation
A systematic review and meta-analysis of cold in situ perfusion and preservation of the hepatic allograft: working towards a unified approach.
Hameed AM, Laurence JM, et al. Liver Transplantation 2017; 22: 22.
Combined resistance and endurance training at a moderate-high intensity improves physical condition and quality of life in liver transplant patients.
Moya-Najera D, Moya-Herraiz A, et al. Liver Transplantation 2017; 27: 27.