{"id":351,"date":"2015-06-12T15:47:40","date_gmt":"2015-06-12T15:47:40","guid":{"rendered":"https:\/\/www.transplantevidence.com\/blog\/?p=351"},"modified":"2015-06-12T15:47:40","modified_gmt":"2015-06-12T15:47:40","slug":"deviation-from-intention-to-treat-analysis-alters-treatment-effect","status":"publish","type":"post","link":"https:\/\/www.transplantevidence.com\/news\/2015\/06\/12\/deviation-from-intention-to-treat-analysis-alters-treatment-effect\/","title":{"rendered":"Deviation from intention-to-treat analysis alters treatment effect"},"content":{"rendered":"<p>A recent article in the BMJ by <a href=\"http:\/\/www.bmj.com\/content\/350\/bmj.h2445\" target=\"_blank\">Abraha et al<\/a>, using large amounts of data from RCTs, has shown that deviation from intention-to-treat analysis (ITT) can lead to apparently larger treatment effects. When compared to standard intention-to-treat analysis there was a significant difference in the apparent treatment effect. When a deviation from ITT was compared to no ITT, there was no significant difference.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>A recent article in the BMJ by Abraha et al, using large amounts of data from RCTs, has shown that deviation from intention-to-treat analysis (ITT) can lead to apparently larger treatment effects. When compared to standard intention-to-treat analysis there was a significant difference in the apparent treatment effect. When a deviation from ITT was compared [&hellip;]<\/p>\n","protected":false},"author":4,"featured_media":0,"comment_status":"open","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[168],"tags":[195,250,274],"class_list":["post-351","post","type-post","status-publish","format-standard","hentry","category-journals","tag-clinical-research","tag-methodology","tag-rct"],"_links":{"self":[{"href":"https:\/\/www.transplantevidence.com\/news\/wp-json\/wp\/v2\/posts\/351","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.transplantevidence.com\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/www.transplantevidence.com\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/www.transplantevidence.com\/news\/wp-json\/wp\/v2\/users\/4"}],"replies":[{"embeddable":true,"href":"https:\/\/www.transplantevidence.com\/news\/wp-json\/wp\/v2\/comments?post=351"}],"version-history":[{"count":0,"href":"https:\/\/www.transplantevidence.com\/news\/wp-json\/wp\/v2\/posts\/351\/revisions"}],"wp:attachment":[{"href":"https:\/\/www.transplantevidence.com\/news\/wp-json\/wp\/v2\/media?parent=351"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/www.transplantevidence.com\/news\/wp-json\/wp\/v2\/categories?post=351"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/www.transplantevidence.com\/news\/wp-json\/wp\/v2\/tags?post=351"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}