Transplant Trial Watch

Randomised controlled trial to evaluate the influence of mHealth and eHealth skin cancer prevention education among young organ transplant recipients: the HIPPOlino intervention study.

Böttcher S, Buck C, et al.

BMJ Open. 2019;9(12):e028842.


Aims
To evaluate whether an SMS-supported personal skin cancer programme leads to a higher increase of preventive knowledge and behavioural change in adolescent organ transplant recipients.

Interventions
All participants received a professional skin examination by a dermatologist and basic training. Intervention group 1 received face-to-face training about sun protection and sun protection recommendations via SMS. Intervention group 2 were given access to a short video. The control group received biannual information about skin care under immunosuppression.

Participants
German speaking organ transplant recipients, aged 5-22 years.

Outcomes
Improvement of behavioural strategies and knowledge regarding UV light prevention.

Follow-up
12 months

CET Conclusions
The HIPPOlino study aim to examine the efficacy of a SMS-supported, multicomponent personal skin cancer prevention education programme compared to an e-learning education programme or waiting list control to increase knowledge and behavioural change in organ transplant recipients aged 5-22 years. The sample size calculations showed that 80 participants per group were needed for a power of 90% and 137 patients were allocated to the groups by computerised randomisation. A self-administered questionnaire assessed the improvement of behavioural strategies and knowledge regarding UV light prevention at 6 weeks, and 6 and 12 months. The study population consisted of 56 children (aged 5-12) and 81 adolescents (aged 13-21), and 82% of participants completed the questionnaire at 12 months. Knowledge of sun protection was low at baseline in all groups. Sun protection knowledge improved in both education programmes compared to the control group at 6 weeks but only in the SMS-supported programme was knowledge significantly improved at 12 months. Sun protection behaviour was more likely to be improved in participants receiving the SMS-supported programme compared to the control group at 6 weeks but not at 6 or 12 months. This underpowered study shows that the SMS-supported programme may improve sun protection knowledge.

Jadad score
3

Data analysis
Per protocol analysis

Allocation concealment
No

Trial registration
Drks00011393

Funding source
Non-industry funded