Transplant Trial Watch

Increasing Organ Donor Designation Rates in Adolescents: A Cluster Randomized Trial.

Rodrigue JR, Boger M, et al.

Am J Public Health. 2019 Sep;109(9):1273-1279


Aims
To evaluate the effectiveness of donation messaging during driver education classes on adolescent organ donor designation rates.

Interventions
An informational versus a testimonial versus a blended (a combination of factual information and personal testimonials) organ donation video messaging interventions.

Participants
Adolescents attending driver education.

Outcomes
The primary outcomes was donor designation rate. Participants were also asked to complete a questionnaire that assessed donor engagement, knowledge, attitude, beliefs, designation likelihood and willingness to discuss donation with parent. Parents were also mailed a questionnaire assessing their donor designation status, donation attitude, adolescent–parent communication about donation, and likelihood of following their adolescent’s donation wishes.

Follow-up
1 week

CET Conclusions
This cluster randomised controlled trial tested the hypothesis that organ donation video messaging in driver education classes would increase donor designation rates among adolescents when compared to a regionally matched historical comparison group. Classrooms were randomised to one of three organ donation video messaging interventions using sealed envelopes that were drawn at random. The messages each lasted approximately 6 minutes and were either informational, testimonial or blended (a combination of factual information and personal testimonials). The matched comparison group typically received a brochure from a regional organ procurement organisation. The primary outcome was participant donor designation when obtaining a driver’s license after the intervention (data from the Department of Transportation) and based on this outcome the power calculation showed that 225 participants per group were needed. The Department of Transportation staff member was blinded however the classroom instructors and research assistants were not blinded. Forty-two classrooms were randomised. The questionnaire completion rates were 100% immediately post-intervention and 57% at the 1-week follow-up. A higher proportion of the study participants registered as a donor when compared to the matched control group (60% vs 50%). More participants registered as donors in the testimonial (64%) and the blended (65%) groups compared to the informational group (51%).

Jadad score
3

Data analysis
Per protocol analysis

Allocation concealment
Yes

Trial registration
ClinicalTrials.gov -NCT03013816

Funding source
Non-industry funded