High-intensity interval training and health-related quality of life in de novo heart transplant recipients - results from a randomized controlled trial.Rolid, K., et al.
Health & Quality of Life Outcomes 2020; 18(1): 283.
The aim of this study was examine the effect of high-intensity interval training (HIT) in comparison to moderate intensity continuous training (MICT) on health-related quality of life (HRQoL) following cardiac transplantation in de novo recipients.
Patients were randomly assigned at a 1:1 ratio to either HIT or MICT.
83 de novo heart transplant patients.
The main endpoint of this study was HRQoL, which was assessed using the SF-36v2.
12 months after heart transplantation
The paper discusses the effect of a high-intensity interval training compared with moderate intensity continuous training on health-related quality of life (HRQoL) in 81 de novo heart transplant recipients who were 7-16 weeks posttransplant. Patients were randomised according to a computer-generated randomisation list and allocation was concealed by using sealed envelopes. HRQoL and symptoms of anxiety and depression (HADS scale) were measured 9 months after randomisation. HRQoL was similar in the study arms at baseline and HADS scores were low. Patients in both groups improved significantly on the HRQoL physical component but there were no significant differences between groups. Scores on the HRQoL mental component and HADS remained the same throughout the study.
ClinicalTrials.gov - NCT01796379