Transplant Trial Watch

Incisional hernias post renal transplant: a systematic review and meta-analysis.

Mac Curtain, B. M., et al.

Hernia 2023 [record in progress].

This study aimed to summarise the current literature on rates, risk factors and outcomes of incisional hernias following renal transplantation.

Electronic databases including PubMed, EMBASE and the Cochrane CENTRAL were searched. Studies were selected independently by two reviewers and data were extracted independently by three reviewers. Risk of bias was assessed using a modified Newcastle–Ottawa scale.

20 studies were included in the review.

The primary outcome was rates of IH. Secondary outcomes included risk factors for IH, and management and outcomes of IH.


CET Conclusions
This systematic review synthesised the available data reporting on the rate and associated risk factors of incisional hernia (IH) after renal transplantation. The authors report on pooled results which are broadly similar to that of other surgical groups, with obesity, smoking and immunosuppression reported as the main risk factors for the development of IH. There are a number of fundamental errors in the statistical analysis. For example, forest plots are used inappropriately to depict cross-sectional data, and the risk of bias tool was modified by the authors resulting in all included studies being rated as ‘good’ or ‘very good’.

Trial registration
PROSPERO - CRD42023441024

Funding source
No funding received