Transplant Trial Watch

To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.

The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].

The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.

Click on each trial for more detail of findings and quality.

April 2018

Kidney transplantation

A prospective randomized, controlled trial of eculizumab to prevent ischemia-reperfusion injury in pediatric kidney transplantation.
Kaabak M, Babenko N, et al. Pediatr Transplant 2018 [record in progress].

A randomized, prospective study of laparoendoscopic single-site plus one-port versus mini laparoscopic technique for live donor nephrectomy.
Lee KW, Choi SW, et al. World Journal of Urology 2018; 02: 02.

Using Social Media for the Promotion of Education and Consultation in Adolescents Who Have Undergone Kidney Transplant: Protocol for a Randomized Control Trial.
Pase C, Mathias AD, et al. JMIR Research Protocols 2018; 7(1): e3.

Liver transplantation

Liver transplantation for alcoholic hepatitis: A systematic review with meta-analysis.
Marot A, Dubois M, et al. PLoS ONE 2018 [Electronic Resource] 13(1): e0190823.

Heart transplantation

Pediatric Heart Donor Assessment Tool (PH-DAT): A novel donor risk scoring system to predict 1-year mortality in pediatric heart transplantation.
Zafar F, Jaquiss RD, et al. Journal of Heart & Lung Transplantation 2018; 37(3): 332-339.

Lung transplantation

Postoperative cognitive dysfunction and mortality following lung transplantation.
Smith PJ, Blumenthal JA, et al. American Journal of Transplantation 2017; 31: 31.

Various organs

Peer Leaders Increase Organ Donor Designation Among Members of Historically African American Fraternities and Sororities.
Loughery C, Zhang N, et al. Progress in Transplantation 2017; 27(4): 369-376.

A Double Blind Randomized Trial of High Dose vs. Standard Dose Influenza Vaccine in Adult Solid Organ Transplant Recipients.
Natori Y, Shiotsuka M, et al. Clinical Infectious Diseases 2018;66(11):1698-1704

Clinical impact of culture-positive preservation fluid on solid organ transplantation: A systematic review and meta-analysis.
Oriol I, Sabe N, et al. Transplantation Reviews 2018;32(2):85-91


Randomized Open Label Cross over Assessment of Prograf vs. Advagraf on Immunosuppressant Pharmacokinetics and Pharmacodynamics in Simultaneous Pancreas Kidney Patients.
Cattral M, Luke S, et al. Clinical Transplantation 2018;32(2):e13180