Transplant Trial Watch

To keep the transplantation community informed about recently published evidence in organ transplantation the Centre for Evidence in Transplantation has developed the Transplant Trial Watch.

The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].

The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.

Click on each trial for more detail of findings and quality.


January 2026

Kidney transplantation

Impact of donor-recipient size mismatch on post-transplant outcomes in kidney transplant recipients: A systematic review.
Asif, S., et al. Transplant Rev (Orlando). 2025 Dec;39(4):100965.

Artificial intelligence-driven kidney organ allocation: systematic review of clinical outcome prediction, ethical frameworks, and decision-making algorithms.
Firuzpour, F., et al. BMC Nephrol. 2025 Nov 14;26(1):639.

Health insurance and kidney transplantation outcomes in the United States: a systematic review and AI-driven analysis of disparities in access and survival.
Garcia Valencia, O. A., et al. Ren Fail. 2025 Dec;47(1):2513007.

A systematic review of simulators for kidney transplantation surgical training.
Kassir, J., et al. Transplant Rev (Orlando). 2025 Dec;39(4):100967.

Safety and Tolerability of Sotagliflozin Among Kidney Transplant Recipients.
McGrath, M. M., et al. Transplantation. 2025 Dec 1;109(12):1887-1895.

Early surgical complications following kidney transplantation in adults: A systematic review.
Ortved, M., et al. Transplant Rev (Orlando). 2025 Dec;39(4):100963.

Exercise-Based Prehabilitation for Kidney Transplant Candidates: the FRAILMar Randomized Controlled Trial.
Pérez-Sáez, M. J., et al. Am J Kidney Dis. 2025 Nov;86(5):634-645.e1.

Liver transplantation

Prognostic and diagnostic biomarkers in liver transplantation: A systematic review and meta-analysis.
Camera, A., et al. Liver Transpl. 2025 Dec 1;31(12):1499-1510.

Heart transplantation

Disparities while listing for orthotopic heart transplantation: A systematic review and meta-analysis.
Phutinart, S., et al Transplant Rev (Orlando). 2025 Dec;39(4):100968.

Various organs

Organ Donor Potential After Extracorporeal Cardiopulmonary Resuscitation for Out-of-Hospital Cardiac Arrest: A Post-Hoc Analysis of a Randomized Controlled Trial.
Verberght, H. C. R., et al. Clin Transplant. 2025 Nov;39(11):e70382.