To keep the transplantation community informed about recently published evidence in organ transplantation the Centre for Evidence in Transplantation has developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
August 2025
Kidney transplantation
Benefits of Anticoagulation Prophylaxis in Children Undergoing Kidney Transplant: Systematic Review and Meta-Analysis.
Al-Huniti, A. H., et al. Journal of Thrombosis & Haemostasis 2025 [record in progress].
Perioperative effects of dexmedetomidine on renal function in allogeneic kidney transplant patients: a meta-analysis.
Guo, Y., et al. International Urology & Nephrology 2025 [record in progress].
Backtable Intra-Arterial Administration of C1 Esterase Inhibitor to Deceased Donor Kidney Allografts Improves Post-Transplant Allograft Function: Results of a Randomized Double-Blind Placebo-Controlled Clinical Trial.
Huang, E., et al. American Journal of Transplantation 2025 [record in progress].
Impact of weight change on kidney transplantation outcomes: A systematic review and meta-analysis.
Kanbay, M., et al. Diabetes, Obesity & Metabolism 2025; 27(3): 1369-1378.
Long-term impact of pregnancy on mortality and graft outcomes in kidney transplant recipients: a systematic review and meta-analysis.
Kanbay, M., et al. International Urology & Nephrology 2025 [record in progress].
12-Month Outcomes of a Prospective Randomized Trial Investigating Effects of IVIG on Top of rATG Versus rATG Alone in Pre-Sensitized Kidney Transplant Recipients: The INHIBIT Study.
Viklicky, O., et al. Transplant International 2025; 38: 14312.
Liver transplantation
Tacrolimus dosing in liver transplant recipients using phenotypic personalized medicine: A phase 2 randomized clinical trial.
Khong, J., et al. Nature communications 2025; 16(1): 4558.
Preoperative carbohydrate loading reduces perioperative insulin resistance and hastens functional recovery of remnant liver after living donor hepatectomy: An open-label randomized controlled trial.
Kumar, M., et al. Hepatology International 2025 [record in progress].
Protective value of ischemia-free liver transplantation on post-transplant acute kidney injury.
Zhao, Q., et al. JHEP Reports : Innovation in Hepatology / EASL 2025; 7(4): 101339.
Lung transplantation
Extracorporeal photopheresis as induction therapy in lung transplantation for cystic fibrosis: a pilot randomized trial.
Righi, I., et al. Frontiers in Immunology 2025; 16: 1583460.