Transplant Trial Watch

To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.

The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].

The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.

Click on each trial for more detail of findings and quality.

May 2017

Kidney transplantation

Successful Cost-Effective Prevention of Cytomegalovirus Disease in Kidney Transplant Recipients Using Low-Dose Valganciclovir.
Gheith O, Halim MA, et al. Experimental & Clinical Transplantation 2017; 15(Suppl 1): 156-163.

Interventions for chronic kidney disease-associated restless legs syndrome.
Gopaluni S, Sherif M, et al. Cochrane Database of Systematic Reviews 2016; 11: CD010690.

Effect of discontinuing morning dose of antihypertensive for renal transplant surgery on haemodynamic and early graft functioning: A prospective, double-blind, randomised study.
Kumar V, Arya VK, et al. Indian Journal of Anaesthesia 2017; 61(2): 150-156.

A comparison of the effects of oral vs. intravenous hydration on subclinical acute kidney injury in living kidney donors: a protocol of a randomised controlled trial.
Mackinnon S, Aitken E, et al. BMC Nephrology 2017; 18(1): 30.

Long-term pulse wave velocity outcomes with aerobic and resistance training in kidney transplant recipients - A pilot randomised controlled trial.
O'Connor EM, Koufaki P, et al. PLoS ONE [Electronic Resource] 2017; 12(2): e0171063.

Effect of Hypothermic Machine Perfusion on the Preservation of Kidneys Donated After Cardiac Death: A Single-Center, Randomized, Controlled Trial.
Wang W, Xie D, et al. Artificial Organs 2017; 08: 08.

Liver transplantation

Multiple Plastic Stents Versus Covered Metal Stent for Treatment of Anastomotic Biliary Strictures after Liver Transplantation: a Prospective, Randomized, Multicenter Trial.
Tal AO, Finkelmeier F, et al. Gastrointest Endosc 2017 [record in progress].

Heart transplantation

Intermediate outcomes with ex-vivo allograft perfusion for heart transplantation.
Chan JL, Kobashigawa JA, et al. Journal of Heart & Lung Transplantation 2017; 36(3): 258-263.

Prediction of Waitlist Mortality in Adult Heart Transplant Candidates: The Candidate Risk Score.
Jasseron C, Legeai C, et al. Transplantation 2017 [record in progress].

Various organs

Outcomes of Solid Organ Transplant Recipients With Preexisting Malignancies in Remission: A Systematic Review and Meta-Analysis.
Acuna SA, Huang JW, et al. Transplantation 2017; 101(3): 471-481.