To keep the transplantation community informed about recently published evidence in organ transplantation the Centre for Evidence in Transplantation has developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
December 2025
Kidney transplantation
A systematic literature review and meta-analysis evaluated modifiable risk factors for the development of BK polyoma virus-associated complications.
Eder, M., et al. Kidney Int. 2025 Oct;108(4):669-685.
A meta-analysis of graft survival, patient survival and delayed graft function in first-time and repeat kidney transplants.
Kanbay, M., et al. Nephrol Dial Transplant. 2025 Sep 29;40(10):1906-1918.
The prevalence and risk factors of erectile dysfunction in kidney transplant recipients: A systematic review and meta-analysis. Medicine (Baltimore).
Liu, X., et al. 2025 Oct 3;104(40):e44509.
Liver transplantation
Use of prothrombin complex concentrates in liver transplantation: a systematic review and meta-analysis.
Kojundzic, I., et al. Br J Anaesth. 2025 Nov;135(5):1172-1192.
Frequency of acute kidney injury in post-liver transplantation and associated factors: a systematic review.
Moura, A. F., et al. J Bras Nefrol. 2025 Oct-Dec;47(4):e20250022.
Quality of Measurement Properties in Patient Reported Outcomes Used in Adult Liver Transplant Candidates and Recipients: a Systematic Review.
van Knippenberg, S. E. M., et al. Transpl Int. 2025 Oct 2;38:14497.
Long-term Follow-up After Hypothermic Oxygenated Machine Perfusion in DCD Liver Transplantation: Results of a Randomized Controlled Multicenter Trial (DHOPE-DCD).
van Rijn, R., et al. Ann Surg. 2025 Nov 1;282(5):717-724.
Heart transplantation
Everolimus and Low-Dose Tacrolimus After Heart Transplant in Children: A Randomized Clinical Trial.
Almond, C. S., et al. Jama. 2025 Oct 21;334(15):1339-1348.
Cognitive Function Among Heart Transplant Recipients Before and After Intravenous Iron Supplement for Iron Deficiency: Results From a Randomized, Placebo-Controlled, Double-Blind Treatment Trial.
Bürker, B. S., et al. Clin Transplant. 2025 Nov;39(11):e70370.
Lung transplantation
Pregnancy Outcomes in 53 Female Lung Transplant Recipients.
Lee, F. G., et al. Chest. 2025 Oct;168(4):932-942.