About Us

Peter Morris

Peter Morris

Founder

Nuffield Department of Surgical Sciences, University of Oxford

Sir Peter Morris, an Australian, was Nuffield Professor of Surgery Emeritus at the University of Oxford and Emeritus Fellow of Balliol College, Oxford. He graduated from the Medical School of the University of Melbourne and St Vincent's Hospital, and received his surgical training in Australia, the UK and the USA. He was a Fellow of the Royal College of Surgeons of England, the Royal Australasian College of Surgeons and the American College of Surgeons. In 1974 he moved from his position as Reader in Surgery at the University of Melbourne to the Nuffield Chair of Surgery and Chairman of Department at the University of Oxford and the Oxford Hospitals and a fellow of Balliol College, positions he held until the end of 2001. In 2001 he was elected as President of The Royal College of Surgeons of England, demitting office in 2004.

After stepping down as President of the Royal College of Surgeons, Sir Peter established the Centre for Evidence in Transplantation (CET), with the aim of evaluating and improving the quality of evidence in solid organ transplantation. Sir Peter stepped down as director of the CET in July 2016, but the work of the centre continues and it has now been renamed to the Peter Morris Centre for Evidence in Transplantation in recognition of his vision and contribution.

Publications

OʼDonoghue KJM, Reed RD, Knight SR, O'Callaghan JM, Ayaz-Shah AA, Hassan S, Weissenbacher A, Morris PJ, Pengel LHM. Critical Appraisal of International Clinical Practice Guidelines in Kidney Transplantation Using the Appraisal of Guidelines for Research and Education (AGREE) II Tool: A Systematic Review. Transplantation 2018; 102(9):1419-1439. [PMID:29787524]

Nasralla D, Coussios CC, Mergental H, Akhtar MZ, Butler AJ, Ceresa CDL, Chiocchia V, Dutton SJ, García-Valdecasas JC, Heaton N, Imber C, Jassem W, Jochmans I, Karani J, Knight SR, Kocabayoglu P, Malagò M, Mirza D, Morris PJ, Pallan A, Paul A, Pavel M, Perera MTPR, Pirenne J, Ravikumar R, Russell L, Upponi S, Watson CJE, Weissenbacher A, Ploeg RJ, Friend PJ; Consortium for Organ Preservation in Europe. A randomized trial of normothermic preservation in liver transplantation. Nature. 2018 May;5 [PMID:29670285]

Macklin PS, Morris PJ, Knight SR. A systematic review of the use of rituximab for the treatment of antibody-mediated renal transplant rejection. Transplantation Reviews 2017; 31(2): 87-95. [PMID:28187998]

O'Donoghue KJM, Reed RD, Knight SR, O'Callaghan JM, Ayaz-Shah AA, Hassan S, Weißenbacher A, Morris PJM, Locke J, Pengel LHM. Critical appraisal of international clinical practice guidelines in kidney transplantation using the Appraisal of Guidelines for Research and Education (AGREE) II tool: A systematic review. 2017 (Accepted Abstract at the BTS Congress, Yorkshire, UK, 1-3 March, 2017).

O’Donoghue KJM, Reed RD, Knight SR, O’Callaghan JM, Ayaz-Shah AA, Hassan S, Morris PJ, Pengel LHM. Systematic review of clinical practice guidelines in kidney transplantation. BJS Open 2017; 1(4): 97–105. [PMID:29951611]

Knight SR, Morris PJ, Schneeberger S, Pengel LH. Trial design and end points in clinical transplant research. Transpl Int. 2016;29(8):870-9 [PMID:26749215]

O'Donoghue KJM, Reed RD, Knight SR, O'Callaghan JM, Morris PJ, Locke J, Pengel LHM. Critical Appraisal of Clinical Practice Guidelines in Kidney Transplantation using the Appraisal of Guidelines for Research and Education (AGREE) II tool: A Systematic Review. 2016. (Poster presentation at the BTS Congress, Glasgow, UK, 24-26 February, 2016).

Knight SR, Metcalfe L, O’Donoghue K, Ball ST, Beale A, et al. (2016) Defining Priorities for Future Research: Results of the UK Kidney Transplant Priority Setting Partnership. PLoS ONE 11(10): e0162136

Morris PJ. Introduction of Jean-Paul Soulillou, MD, Recipient of the 2016 Medawar Prize. Transplantation. 2016 Dec;100(12):2495-2497. [PMID:27861279]

O'Callaghan JM, Knight SR, Morgan RD, Morris PJ. A National Registry Analysis of Kidney Allografts Preserved With Marshall's Solution in the United Kingdom. Transplantation. 2016 Nov;100(11):2447-2452. [PMID:26760566]

Morris PJ. Sir Peter J. Morris, AC, FRS: Melbourne and Oxford Universities' transplantation surgeon and retiring editor of Transplantation, 1976-2014. Transplantation. 2015 Apr;99(4):651-3. doi: 10.1097/TP.0000000000000713. [PMID:25827322]

Macklin PS, Morris PJ, Knight SR. A systematic review of the use of rituximab as induction therapy in renal transplantation. Transplant Rev. 2015; 29(2):103-8. [PMID:25555541]

Pengel LHM, Knight SK, Morris PJ. Transplant Library - the definitive resource of high quality evidence in solid organ. RCS Annual Day 2014 and SITU’s Launch, March 26, 2014, University of Oxford, UK.

O'Callaghan JM, Morgan RD, Knight SR and Morris PJ. The Effect of Preservation Solutions for Storage of Liver Allografts on Transplant Outcomes: A Systematic Review and Meta-analysis. Annals of Surgery. 2014 Jul; 260(1):46-55 [PMID:24374537]

Som R, Morris PJ and Knight SR. Graft Vessel Disease Following Heart Transplantation: A Systematic Review of the Role of Statin Therapy. World Journal of Surgery 2014; DOI:10.1007/s00268-014-2543-x [PMID:24700094]

MacKlin P, Morris PJ and Knight SR. A Systematic Review of the Use of Rituximab for Desensitization in Renal Transplantation. Transplantation 2014; 98(8):794-805 [PMID:25321163]

Evans JDW, Morris PJ and Knight SR. Antifungal Prophylaxis In Liver Transplantation: A Systematic Review And Network Meta-Analysis. American Journal of Transplantation 2014;14(12):2765-76 [PMID:25395336]

Monaco AP, Morris PJ. Reverence for the Organ Donor. Transplantation 2014; 97(11):1089 [PMID:24804997]

O'Callaghan J, Leuvenink H, Friend P, Ploeg R. Kidney Preservation, Chapter 9 in: Kidney Transplantation, Principles and Practice 7th Edition. Saunders. Eds Peter J Morris and Stuart J Knechtle. p130-141

O'Callaghan J, Knight S, Morgan R, Morris P. A national registry analysis of kidney allograft preservation with Marshall's Solution in the United Kingdom (Poster presentation at the World Transplant Congress, San Francisco, 2014)

O'Callaghan J, Knight S, Morgan R, Morris P. A national registry analysis of kidney allograft presentation with Marshall's Solution in the United Kingdom. (Oral at the British Transplantation Society, Glasgow 2014)

Monaco AP, Morris PJ. Editors' commentary: the Asian contribution to living donor liver transplantation. Transplantation. 2014 Apr 27;97 Suppl 8:S1. doi: 10.1097/TP.0000000000000157. [PMID:24694463]

Editorial commentary: Increasing focus on antibodies. Transplantation. 2014 Aug 15; 98 (Suppl 3): S1-2. [PMID:25093440]

Morris PJ. Transplantation at a Glance. Transplantation 2013; 95(11): 1

Liu, LQ, Morris PJ, et al. Compliance to the CONSORT statement of randomized controlled trials in solid organ transplantation: a 3-year overview. Transplant International 2013; 26(3): 300-306. [PMID:23279054]

O'Callaghan JM, Morgan RD, Knight SR, Morris PJ. Systematic review and meta-analysis of hypothermic machine perfusion versus static cold storage for kidney allografts on transplant outcomes. British Journal of Surgery. 2013 Jul; 100(8):991-1001. [PMID:23754643]

O'Callaghan J, Morgan R, Knight S, Morris P. Systematic reviews of alemtuzumab in renal transplantation. Transplant Immunology. March 2013; 28 (2): 71. [PMID:23352935]

Pengel LHM, Knight S, Emin A, O’Callaghan J, Van der Meulen J, Papalois V, Morris PJ. How to teach evidence-based skills in 1.5 days: the Evidence in Transplantation (EVIT) Course. 16th Congress of the European Society for Organ Transplantation, September 8-11, 2013, Vienna, Austria

Morris PJ. Joseph E. Murray (1919-2012). Nature 2013; 493(7431): 164

Pengel LHM, Morris PJ. Transplant Library - the definitive resource of high quality evidence in solid organ. Evidence Live, March 25-26, 2013, University of Oxford, UK.

Macklin P,Knight S, Morris P. A systematic review of rituximab as desensitisation therapy in renal transplantation. (Poster presentation at the Joint British Transplantation Society and Renal Association Congress, Bournemouth, March 2013)

O'Callaghan J, Morgan R, Knight S, Morris P.Preservation solutions for static cold storage of liver allografts: A systematic review and meta-analysis. 16th Annual Congress of the British Transplantation Society, Bournemouth, 2013.

Morris PJ. Comment on "Hartman Stahelin (1925-2011) and the contested history of cyclosporine A". Clinical Transplantation 2013; 27(3):325 [PMID:23621756]

Kidney Transplantation: Principles and Practice. 2014. 7th edition. Eds. Peter J Morris and Stuart J Knechtle. Elsevier, Philadelphia

Morris P J. Azathiaprine in Kidney Transplantation: Principles and Practice, 7th edition. Eds. P J Morris and Stuart J Knechtle, Elsevier, Philadelphia. p216-220

Knight SR, Pengel LHM, Morris PJ. Chapter 42: Evidence in Transplantation in Kidney Transplantation: Principles and Practice. 7th edition. Eds. P. J. Morris and Stuart J Knechtle, Elsevier, Philadelphia. p729- 736

O'Callaghan J, Morgan R, Knight S, Morris P. Liver allograft preservation fluids: A systematic review and meta-analysis. Transplant International. 2013; 26(Supp s2):332

Pengel LHM, Knight S, Emin A, O'Callaghan J, Van der Meulen J, Papalois V, Morris P. How to teach evidence-based practice skills in 1.5 days: the Evidence in Transplantation (EVIT) course. Transplant International. 2013; 26(Supp s2);192

O'Callaghan J, Morgan R, Knight S, Morris P. Liver allograft preservation fluids: A Systematic review and Meta-Analysis. (Poster presentation at the European Society for Organ Transplantation, Vienna 2013)

Pengel L, Knight S, Emin A, O'Callaghan J, Van der Meulen J, Papalois V, Morris P. How to teach evidence-based practice skills in 1.5 days: The Evidence in Transplantation (EVIT) Course. (Poster presentation at the European Society for Organ Transplantation, Vienna 2013)

Morris P, Monaco A. Lasker-DeBakey Awards for Sir Roy Calne and Thomas Starzl. Transplantation. January 27 2013; 95(2):266

O'Callaghan JM, Knight SR, Morgan RD, Morris PJ. Preservation solutions for static cold storage of kidney allografts: a systematic review and meta-analysis. American Journal of Transplantation 2012; 12(4): 896-906. [PMID:22221739]

Morgan RD, O'Callaghan JM, Knight SR, Morris PJ. Alemtuzumab induction therapy in kidney transplantation: a systematic review and meta-analysis. Transplantation 2012; 93(12): 1179-1188 [PMID:22660659]

Zucker K, Pengel LH*, Liu LQ, Morris PJ. The Rate of Publication of Abstracts in Solid Organ Transplantation Presented at Scientific Meetings. 24th International Congress of The Transplantation Society, July 15 - 19, 2012, Berlin, Germany. * presenting author

O’Callaghan J, Morgan R, Knight S, Morris P. Hypothermic machine preservation in comparison with static cold storage for kidney allografts. The Transplantation Society Congress, Berlin 2012

Morgan RD*, O’Callaghan JM, Knight SR, Morris PJ. Alemtuzumab induction therapy in kidney transplantation: a systematic review and meta-analysis. 24th International Congress of The Transplantation Society, Berlin, Germany. * presenting author

Liu LQ*, Pengel L and Morris PJ. Do Reports Of Randomised Controlled Trials In Solid Organ Transplantation Adhere To The 2010 CONSORT Statement? A 3-year Overview. 15th Annual Congress of the British Transplantation Society in Glasgow, 22nd-24th Feb, 2012. * presenting author

Morris PJ. University of Melbourne Medical School: reflections of a graduate. The Medical Journal of Australia 2012; 197(5): 301-2 [PMID:22938131]

Morgan R, O'Callaghan J, Knight S, Morris P. Alemtuzumab induction therapy in kidney transplantation: A Systematic Review and Meta-Analysis. Transplantation. 2012; 94(10S):972

O'Callaghan J, Morgan R, Knight S, Morris P. Hypothermic machine preservation in comparison with static cold storage for kidney allografts: A Systematic review and Meta-Analysis. Transplantation. 2012; 94(10S):277

Monaco AP, Morris PJ. Donor disease transmission: minimizing the risks and maximizing the benefits. Transplantation. 2012 Mar 15;93(5 Suppl):S1-3. doi: 10.1097/TP.0b013e31824f3d9c. [PMID:22374264]

Knight SR, Morris PJ. Steroid avoidance or withdrawal in renal transplantation. Transplantation 2011; 91(5):e25; author reply e26-7 [PMID:21336081]

Monaco AP, Morris PJ. Everolimus and long-term outcomes in renal transplantation:seeking an opimal strategy for immunosuppression. Transplantation. 2011; 92(3 Suppl): S1-2 [PMID:21799391]

Monaco AP, Morris PJ. Chronic renal allograft damage: not enough immunosuppression? Transplantation. 2011; 91(9 Suppl): S1-3 [PMID:21519212]

Morris PJ. An Obituary: Baruch Samuel Blumberg. Oxford Medicine. 2011, July

Pengel LHM, Liu LQ, Morris PJ. Do wound complications or lymphoceles occur more often in solid organ transplant recipients on mTOR inhibitors? A systematic review of randomized controlled trials. Transplant International 2011; 24(12):1216-1230 [PMID:21955006]

Knight SR, Morris PJ. Steroid sparing protocols following nonrenal transplants; the evidence is not there. A systematic review and meta analysis. Transplant International 2011; 24(12): 1198-1207 [PMID:21923805]

Pengel L, Morris P. The Transplant Library of randomized controlled trials and systematic reviews. Transplantation 2011; 92(6):613-6 [PMID:21866077]

Knight SR, Morris PJ. Interaction between maintenance steroid dose and the risk/benefit of steroid avoidance and withdrawal regimens following renal transplantaion. Transplantation 2011; 92(11): e63-4

O’Callaghan J, Knight S, Morgan R, Morris P. Preservation solutions for static cold storage of kidney allografts. Oral- European Society of Organ Transplantation, Glasgow 2011

Liu LQ*, Pengel L and Morris PJ. Reporting of quality of randomised controlled trials in solid organ transplantation. ESOT Congress. Glasgow, 4-7th September 2011. * presenting author

O'Callaghan J, Morgan R, Knight S, Morris P. Preservation solutions for static cold storage of kidney allografts: A Systematic Review and Meta-Analysis. Transplant International. 2011; 24(s2):204

Knight SR and Morris PJ. Steroid avoidance or withdrawal following renal transplantation increases the risk of acute rejection but decreases cardiovascular risk. A meta-analysis. Transplantation 2010. Jan 15; 89 (1): 1-14 [PMID:20061913]

Morris PJ. Organ Transplantation: a medical miracle of the 20th century. The Order (National Magazine for the Order of Australia Association) 2010; 22:6.

Currie AC, Knight SR and Morris PJ. Tuberculosis in Renal Transplant Recipients: The Evidence for Prophylaxis. Transplantation 2010; 90(7): 695-704 [PMID:20647975]

Morris PJ and Monaco AP. Outcome and allocation of deceased heart-beating donor kidneys in the United kingdom. Transplantation 2010;89(4):371 [PMID:20177336]

Morris J and Morris PJ. Sunday's child? A memoir by Leslie Baruch Brent. Transplantation 2010;89(3):267-9 [PMID:20145514]

Morris PJ. Kidneys donated after cardiac death are acceptable. Lancet 2010; 376(9749): 1276-8. [PMID:20727577]

Bradley JA, Hardy M, Neuberger J, Sachs D, Suthanthiran M, Wood K, Monaco AP, Morris PJ. Transplantation: a report of progress. Transplantation 2010; 90(12); 1245 [PMID:21160404]

Morris PJ and Monaco AP. Jean Dausset (1916-2009): a Scientist and Man for all Seasons. Transplantation 2009; 88(11) 1240-1241

Pengel L, Barcena L and Morris PJ. Quality of reporting of randomised controlled trials in organ transplantation. Transplant International 2009; 22(4):377-84 [PMID:19000234]

Knight SR, Russell NK, Barcena L, Morris PJ. Mycophenolate mofetil decreases acute rejection and may improve graft survival. A systematic review. Transplantation 2009;87(6):785-94 [PMID:19300178]

Barcena L, Pengel L and Morris PJ. Searching the transplantation library. Transplantation. 2008 Apr 27;85(8):1068-74. [PMID:18431222]

Barry JM and Morris PJ. Surgical Techniques of Renal Transplantation in Kidney Transplantation: Principles and Practice 6th Edition (eds. Morris PJ & Knechtle S), 2008: p158

Knight SR, Morris PJ. Azathioprine and Steroids in Kidney Transplantation: Principles and Practice 6th Edition (eds. Morris PJ & Knechtle S), 2008: p220

Russell NK, Knight SR and Morris PJ. Cyclosporine in Kidney Transplantation: Principles and Practice 6th Edition (eds. Morris PJ & Knechtle S), 2008: p234

Knechtle SJ and Morris PJ. Results of Renal Transplantation in Kidney Transplantation: Principles and Practice 6th Edition (eds. Morris PJ & Knechtle S), 2008: p657

Morris PJ, Knechtle SJ. (Editors) Kidney Transplantation: Principles and Practice. 6th Edition (Elsevier, Philadeliphia) 2008

Morris PJ and Monaco AP. Evidence in transplantation: randomized versus nonrandomized studies. Transplantation 2008; 86(1): 16-7 [PMID:18622270]

Knight SR and Morris PJ. Does the evidence support the use of Mycophenolate Mofetil therapeutic drug monitoring in clinical practice? A systematic review. Transplantation 2008; 85(12): 1675-1685. [PMID:18580456]

Monaco A, Morris PJ. Intestinal transplantation comes of age. Transplantation 2008 May 15;85(9):1221 [PMID:18475174]

Morris PJ, Ploeg RJ. Help in the design and reporting of randomized controlled trials: a collaboration between ESOT and CET towards a knowledge centre for European transplantations. Transpl Int. 2008 Jun;21(6):511

Knight SR and Morris PJ. In response to: Benefit of neoral C2 monitoring in de novo cardiac transplant recipients receiving basiliximab induction. Transplantation 2008 Sep 27;86(6):885 [PMID:18813115]

Morris PJ. Academic surgery in the United Kingdom. ANZ J Surg. 2008 May;78(5):341-2 [PMID:18380725]

Morris PJ . A history of renal transplantation. Journal of the British Renal Association 2008.

Pengel L, Barcena L, Morris PJ*. Quality of reporting of randomized controlled trials in solid organ transplantation. 22nd Congress of the Transplantation Society, August 10 -14, 2008, Sydney, Australia. * presenting author

Morris PJ, Monaco AP, Mulligan J. Instant electronic access to randomized controlled trials (RCT). Transplantation. 2007 Oct 27;84(8):939 [PMID:17989594]

Monaco AP, Morris PJ. Editorial comment: a role for alloimmune response mediators in tolerance induction? Transplantation. 2007 Jul 15;84(1 Suppl):S1-2 [PMID:17632404]

Knight, SR, Friend PJ, Morris PJ (2007) Role of transplantation in the management of hepatic malignancy. Brit J. Surg. 2007; 94(11) : 1319-30 [PMID:17939138]

Knight SR and Morris PJ. The clinical benefits of cyclosporine C2-level monitoring: a systematic review. Transplantation 2007; 83(12):1525-35 [PMID:17589331]

Pengel L, Barcena L and Morris PJ. Registry of randomized controlled trials in transplant ation: January 1 to June 30, 2006. Transplantation 2007; 83(8): 1001-14 [PMID:17452884]

Morris P, Bradley A, Doyal, L et al. Face Transplantation: a review of the technical, immunological, psychological and clinical issues with recommendations for good practice. Transplantation 2007; 83(2):109 [PMID:17264807]

Itani KM, Morris PJ, Macias FC, Bevilacqua RG, Cheng SW, Ladipo JK, Brennan MF. Training of a surgeon: an international perspective. J Am Coll Surg 2007 Mar;204(3):478-85 [PMID:17324785]

Pengel L, Barcena L, Morris PJ (2007). Registry of randomized controlled trials in transplantation: July 1 to December 31, 2006. Transplantation 84 (8): 940-953 [PMID:17989595]

Morris PJ. Medawar prize acceptance speech. Transplantation 2006 Dec 27;82(12):1590-5 [PMID:17198241]

Bradley JA, Hardey M, Neuberger, J, Sachs D, Suthanthiran M, Wood K, Monaco AP and Morris PJ. Transplantation: a report of progress. Transplantation 2006 Dec 27, 82(11):1410

Morris PJ. Rene Kuss (1913-2006). Transplantation 2006 Dec 15;82(11):1410 [PMID:17164708]

Morris PJ and Russel NK. Alemtuzumab (Campath-1H): A Systematic Review in Organ Transplantation. Transplantation. 2006 May 27;81(10):1361-1367 [PMID:16732169]

Pengel L, Barcena L and Morris PJ. Registry of Randomized Controlled Trials in Transplantation: July 1 to December 31, 2005. Transplantation 2006; 82(10):1247-1260 [PMID:17130770]

Morris PJ, Bradley A, Doyal L, Earley M, Milling M, Rumsey N. Facial Transplantation: Working Party Report. 2006 (2nd edition). www.rcseng.ac.uk

Monaco AP and Morris PJ. Editorial comment: the other consequences of CMV infection. Transplantation 2006; 82(8 Suppl):S1-2 [PMID:16858267]

Morris PJ. Biomedical Industrial Sponsorship and its impact on the Medical Literature. World Journal of Surgery 2006; 30(8):1371-1373 [PMID:16773249]

Goosen J, Morris PJ, Kobusingy O, Mock C. Essential Trauma Care through the Partner Organizations: IATSIC, ISS-SIC and WHO. World Journal of Surgery 2006; 30(6):940-945 [PMID:16736319]

Morris PJ, Monaco AP. Costs of ABO incompatible living donor transplantation are justified. Transplantation 2006; 82(2):154 [PMID:16858273]

Monaco AP and Morris PJ. The Fifth Beaune Symposium: focus on the vascular endothelium in organ transplantation. Transplantation 2006; 82(1 Suppl):S1-2 [PMID:16829786]

Morris PJ. Norman Shumway: the Quiet Pioneer of Cardiac Transplantation (1923 - 2006). Transplantation 2006; 81(9):1225-1226

Pengel L, Barcena L and Morris PJ. Registry of Randomized Controlled Trials in Transplantation: January 1 to June 30, 2005 . Transplantation 2006; 81(8):1071-1086 [PMID:16641590]

Barcena L, Pengel LHM*, Morris PJ. The quality of randomized trials in organ transplantation must be improved. Transplantation 82(1 suppl3): 467-468. World Transplant Congress, July 22 - 27, 2006, Boston, USA. * presenting author

Barcena L, Pengel L and Morris PJ . Registry of Randomized Controlled Trials in Transplantation. Transplantation 2005; 80(11):1525-1527 [PMID:16371918]

Pengel L, Barcena L, Morris PJ . Registry of randomized controlled trials in transplantation Transplantation 2005; 80(4):432 [PMID:16123713]

Morris PJ. Quality of Randomized Trials in Solid Organ Transplantation. Transplantation 2005; 80(4):431 [PMID:16123712]

Morris PJ, Monaco AP. Pancreatic islet transplantation: is the glass half-empty or half-full? Transplantation 2005; 79 (10):1287-8 [PMID:15912089]

Monaco AP and Morris PJ. Care of the live kidney donor: consensus on the ultimate gift. Transplantation 2005; 79(6 suppl 2):S51 [PMID:15785360]

Morris PJ, Monaco AP. Reduction in calcineurin inhibitor exposure and maintenance of effective immunosuppression: clinical experience with everolimus (Certican). Transplantation 2005; 79(1 Suppl):S67-8 [PMID:15880017]

Morris PJ. Sir Michael Francis Addison Woodruff. Biogr.Mems.Fell.R.Soc. 2005; 51: 444-471

Morris PJ. Transplantation - a medical miracle of the 20th century. N Engl J Med 2004; 351(26):2678-80 [PMID:15616201]