To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
Belimumab in kidney transplantation: an experimental medicine, randomised, placebo-controlled phase 2 trial.
Banham GD, Flint SM, et al. Lancet 2018 [record in progress]
The Effect of Antithymocyte Globulin and Everolimus on the Kinetics of Cytomegalovirus Viral load in Seropositive kidney Transplant Recipients without prophylaxis.
Basso G, Felipe CR, et al. Transplant Infectious Disease 2018 [record in progress]
Limited Sampling Strategy for Estimating Mycophenolic Acid Exposure on Day 7 Post-Transplant for Two Mycophenolate Mofetil Formulations Derived From 20 Chinese Renal Transplant Recipients.
Cai W, Cai Q, et al. Transplantation Proceedings 2018 [record in progress]
The effect of the use of a TNF-alpha inhibitor in hypothermic machine perfusion on kidney function after transplantation.
Diuwe P, Domagala P, et al. Contemporary Clinical Trials 2017; 59: 44-50.
Outcomes at 7 years post-transplant in black vs nonblack kidney transplant recipients administered belatacept or cyclosporine in BENEFIT and BENEFIT-EXT.
Florman S, Vincenti F, et al. Clinical Transplantation 2018; 32(4): e13225.
The effect of spironolactone on calcineurin inhibitor induced nephrotoxicity: a multicenter randomized, double-blind, clinical trial (the SPIREN trial).
Mortensen LA, Thiesson HC, et al. BMC Nephrology 2018; 19(1): 105.
Five-year outcomes in kidney transplant patients randomized to everolimus with cyclosporine withdrawal or low-exposure cyclosporine versus standard therapy.
Sommerer C, Duerr M, et al. American Journal of Transplantation 2018 [record in progress]
Effect of Magnesium Supplements on Insulin Secretion After Kidney Transplantation: A Randomized Controlled Trial.
Van Laecke S, Caluwe R, et al. Annals of Transplantation 2017; 22: 524-531.
Smoking and outcomes in kidney transplant recipients: a post hoc survival analysis of the FAVORIT trial.
Weinrauch LA, Claggett B, et al. International Journal of Nephrology & Renovascular Disease 2018; 11: 155-164.
Renal effects of norepinephrine-induced variations in mean arterial pressure after liver transplantation: A randomized cross-over trial.
Skytte Larsson J, Bragadottir G, et al. Acta Anaesthesiologica Scandinavica 2018; 12: 12.