Transplant Trial Watch

To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.

The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].

The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.

Click on each trial for more detail of findings and quality.

February 2020

Kidney transplantation

Systematic Review and Meta-Analysis of Asymptomatic Bacteriuria After Renal Transplantation: Incidence, Risk of Complications and Treatment Outcomes.
Gomez-Ochoa, S. A. and A. Vega-Vera (2019). Transplant Infectious Disease [record in progress].

A prospective, randomized, pilot trial of a polyethylene glycol (PEG)-coated collagen patch for intraoperative hemostasis during deceased donor renal transplant.
Kapoor, A., et al. (2019). Canadian Urological Association Journal [record in progress].

Patient Survival Following Renal Transplantation in Indigenous Populations: A Systematic Review.
McGuire, C., et al. (2019). Clinical Transplantation [record in progress].

Direct Delivery of Kidney Transplant Education to Black and Low-Income Patients Receiving Dialysis: A Randomized Controlled Trial.
Waterman, A. D., et al. (2019). American Journal of Kidney Diseases 74(5): 640-649.

Heart transplantation

Risk prediction models for survival after heart transplantation: A systematic review.
Aleksova, N., et al. (2019). American Journal of Transplantation [record in progress].

Lung transplantation

Efficacy and safety of the combination of reduced duration prophylaxis followed by immuno-guided prophylaxis to prevent cytomegalovirus disease in lung transplant recipients (CYTOCOR STUDY): an open-label, randomised, non-inferiority clinical trial.
Paez-Vega, A. et al. (2019). BMJ Open 9(8): e030648.

Various organs

Drug-Drug Interaction Study of Apixaban with Cyclosporine and Tacrolimus in Healthy Volunteers.
Bashir, B., et al. (2018). Clinical and translational science 11(6): 590-596.

Daylight photodynamic therapy for prevention of new actinic keratosis and keratinocyte carcinomas in organ transplants. A cryotherapy-controlled randomized clinical trial.
Bernad, I., et al. (2019). Journal of the European Academy of Dermatology & Venereology [record in progress].

Cell-Mediated Immune Responses after Influenza Vaccination of Solid Organ Transplant Recipients: a Secondary Outcomes Analysis of a Randomized Controlled Trial.
L'Huillier, A. G., et al. (2019). Journal of Infectious Diseases [record in progress].

Efficacy and safety of tacrolimus in de novo pediatric transplant recipients randomized to receive immediate- or prolonged-release tacrolimus.
Vondrak, K. et al. (2019). Clinical Transplantation [record in progress].