To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
Posttransplant reduction in preexisting donor-specific antibody levels after belatacept- versus cyclosporine-based immunosuppression: Post hoc analyses of BENEFIT and BENEFIT-EXT.
Bray RA, Gebel HM, Townsend R, et al Am J Transplant. 2018; 18:1774-82.
The impact of everolimus in reducing cytomegalovirus events in kidney transplant recipients on steroid-avoidance strategy: 3-year follow-up of a randomized clinical trial
de Sandes-Freitas TV, Pinheiro PMA, et al Transpl Int. 2018; [record in progress]
Hand-Assisted laparoscopic donor nephrectomy PERiumbilical versus Pfannenstiel incision and return to normal physical ACTivity (HAPERPACT): study protocol for a randomized controlled trial.
Kulu Y, Muller-Stich BP, Ghamarnejad O, et al. Trials. 2018; 19:377
Paricalcitol versus placebo for reduction of proteinuria in kidney transplant recipients: a double-blind, randomized controlled trial
Oblak M, Mlinšek G, Kandus A, et al Transpl Int. 2018 [record in progress]
Nephrectomy Versus Embolization of Non- Functioning Renal Graft: A Systematic Review with a Proportional Meta-Analysis
Takase HM, Contti MM, Nga HS, et al. Ann Transplant. 2018; 23:207-217.
Donor dopamine does not affect liver graft survival: Evidence of safety from a randomized controlled trial.
Benck U, Jung M, Krüger B, et al Liver Transpl. 2018; [record in progress]
α-lipoic acid reduces postreperfusion syndrome in human liver transplantation - a pilot study
Casciato P, Ambrosi N, Caro F, et al. Transpl Int. 2018; [record in progress]
SEALIVE: the use of technical vessel-sealing devices for recipient hepatectomy in liver transplantation: study protocol for a randomized controlled trial.
Houben P, Khajeh E, Hinz U, et al. Trials 19: 380.
Once- daily, prolonged- release tacrolimus vs twice- daily, immediate- release tacrolimus in de novo living- donor liver transplantation: A Phase 4, randomized, open- label, comparative, single- center study.
Shin MH, Song GW, Lee SG, et al. Clin Transplant. 2018; [record in progress]
Global prevalence of resistant hypertension: a meta-analysis of data from 3.2 million patients.
Noubiap JJ, Nansseu JR, Nyaga UF, et al. Heart. 2018; [record in progress]