To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
May 2025
Kidney transplantation
A structured, home-based exercise programme in kidney transplant recipients (ECSERT): A randomised controlled feasibility study.
Billany, R. E., et al PLoS ONE [Electronic Resource] 2025; 20(2): e0316031.
Comparison of Magnetic and Conventional Double-J Stent Following Kidney Transplantation: A Randomized Controlled Trial.
Glienke, M., et al. Transplantation Direct 2025; 11(4): e1773.
Calcitriol Supplementation After Kidney Transplantation: Results of a Double-Blinded, Randomized, Placebo-Controlled Trial.
Khairallah, P., et al. Journal of Bone & Mineral Research 2025 [record in progress].
Comparison of analgesic efficacy of continuous transversus abdominis plane (TAP) block with continuous epidural analgesia in renal transplant recipients.
Ojha, H., et al. Saudi Journal of Anaesthesia 2025; 19(1): 45-51.
Short-term fasting before living kidney donation has an immune-modulatory effect.
Oudmaijer, C. A. J., et al. Frontiers in Immunology 2025; 16: 1488324.
Liver transplantation
Oral LPCN 1148 improves sarcopenia and hepatic encephalopathy in male patients with cirrhosis: A randomized, placebo-controlled phase 2 trial.
Bruno, B. J., et al. Hepatology 2025 [record in progress].
Home-based exercise and PHysical activity maintenance interventiOn after livEr traNsplantation: Impact of eXercise intensity (PHOENIX-Liver).
De Smet, S., et al. BMJ Open Sport & Exercise Medicine 2025; 11(1): e002436.
Impact of differential glycemic management goals in pre-anhepatic and anhepatic phase on early grafted liver function after liver transplantation: An open-label, randomized, controlled study.
Duan, Y., et al. Journal of Clinical Anesthesia 2025; 103: 111807.
Comparing the efficacy and safety of thromboprophylaxis with enoxaparin versus normal saline after liver transplantation: randomized clinical trial.
Xie, K., et al. British Journal of Surgery 2025; 112(2): 01.
Heart transplantation
Donation after circulatory death transplantation: a systematic review and meta-analysis of outcomes and methods of donation.
Jolliffe, J., et al. Annals of Cardiothoracic Surgery 2025; 14(1): 11-27.