Transplant Trial Watch

To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.

The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].

The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.

Click on each trial for more detail of findings and quality.


November 2024

Kidney transplantation

Right and left living donor nephrectomy and operative approach: A systematic review and meta-analysis of donor and recipient outcomes.
Calpin, G. G., et al. Transplantation Reviews 2024 [record in progress].

Nudging the nudger: Performance feedback and organ donor registrations.
House, J., et al. Journal of Health Economics 2024; 97: 102914.

A randomized, placebo-controlled, dose-escalation phase I/II multicenter trial of low-dose cidofovir for BK polyomavirus nephropathy.
Imlay, H., et al. Transplant Infectious Disease 2024 [record in progress].

Effect of an exercise intervention or combined exercise and diet intervention on health-related quality of life-physical functioning after kidney transplantation: the Active Care after Transplantation (ACT) multicentre randomised controlled trial.
Knobbe, T. J., et al. The Lancet Healthy Longevity 2024 [record in progress].

Effect of an intensive nutrition intervention of a high protein and low glycemic load diet on weight of kidney transplant recipients: a randomized clinical trial.
Pedrollo, E. F., et al. Endocrine 2024 [record in progress].

Liver transplantation

Safety of acamprosate for alcohol use disorder Post-Liver transplant: a pilot randomized controlled trial.
Ayyala-Somayajula, D., et al. Liver Transplantation 2024 [record in progress].

Hypothermic oxygenated machine perfusion influences the immunogenicity of donor livers in humans.
Elgosbi, M., et al. Liver Transplantation 2024 [record in progress].

The Effect of Enhanced Recovery After Surgery Nursing on the Recovery in Patients After Liver Transplantation.
Hu, Z. and D. Li Transplantation Proceedings 2024; 56(7): 1617-1623.

Heart transplantation

Apixaban in bridge to transplant and destination LVAD - rationale and study design: the ApixiVAD trial.
Schnegg, B., et al. ESC heart failure 2024; 11(4): 2387-2394.

Various organs

Effectiveness of remote ischemic preconditioning in patients undergoing transplant surgery: meta-analysis of randomized control studies.
Abbas, A. F., et al. Annals of Medicine & Surgery 2024; 86(9): 5455-5460.