Transplant Trial Watch

To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.

The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].

The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.

Click on each trial for more detail of findings and quality.

October 2020

Kidney transplantation

Home-based inspiratory muscle training in pediatric patients after kidney transplantation: a randomized clinical trial
Carbonera, R. P., et al. Pediatric Nephrology 2020; 35(8): 1507-1516.

A Randomized Prospective Study Comparing Anti-T-Lymphocyte Igs to Basiliximab in Highly Sensitized Kidney Transplant Patients.
Kamar, N., et al. KI Reports 2020; 5(8): 1207-1217.

Comparison of a magnetic retrieval device vs. flexible cystoscopy for removal of ureteral stents in renal transplant patients: A randomized controlled trial.
Kapoor, A., et al. Canadian Urological Association Journal 2020 [record in progress].

Educational Animations to Inform Transplant Candidates About Deceased Donor Kidney Options: An Efficacy Randomized Trial.
Kayler, L. K., et al. Transplantation Direct 2020; 6(7): e575.

Efficacy and safety of chemical thromboprophylaxis in renal transplantation - A systematic review.
Kohli, R., et al. Thrombosis Research 2020; 192: 88-95.

Mannitol and renal graft injury in patients undergoing deceased donor renal transplantation - a randomized controlled clinical trial.
Reiterer, C., et al. BMC Nephrology 2020; 21(1): 307.

Liver transplantation

The Impact of COVID-19 Global Pandemic on Morbidity and Mortality of Liver Transplant Recipients Children and Adults: A Systematic Review of Case Series.
Gavriilidis, P. and M. Pai Journal of Clinical Medicine Research 2020; 12(7): 404-408.

Liver transplantation in hepatocellular carcinoma after tumour downstaging (XXL): a randomised, controlled, phase 2b/3 trial.
Mazzaferro, V., et al. Lancet Oncology 2020; 21(7): 947-956

Lung transplantation

Effect of high-intensity training on peak oxygen uptake and muscular strength after lung transplantation: A randomized controlled trial.
Ulvestad, M., et al. Journal of Heart & Lung Transplantation 2020; 39(9): 859-867.

Various organs

Daily use of a muscle pump activator device reduces duration of hospitalization and improves early graft outcomes post-kidney transplantation: A randomized controlled trial.
Xie, W., et al. Canadian Urological Association Journal 2020 [record in progress].