Transplant Trial Watch

To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.

The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].

The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.

Click on each trial for more detail of findings and quality.

April 2019

Kidney transplantation

Web-Based Tailored Intervention to Support Optimal Medication Adherence Among Kidney Transplant Recipients: Pilot Parallel-Group Randomized Controlled Trial.
Cote, J., Fortin, M. C. et al. (2018). JMIR Formative Research 2(2): e14.

Genetic markers associated with long-term cardiovascular outcome in kidney transplant recipients.
Pihlstrøm, H. K., Mjøen, G. et al. (2018). Am J Transplant; [record in progress].

Liver transplantation

Liver transplantation in elderly patients: a systematic review and first meta-analysis.
Gomez Gavara, C., Esposito, F et al. (2019). HPB 21(1): 14-25.

Effects of quadriceps muscle neuromuscular electrical stimulation in living donor liver transplant recipients: phase-II single-blinded randomized controlled trial.
Hanada, M., Soyama, A. et al. (2019). Clinical Rehabilitation [record in progress].

Clamp-Crush Technique Versus Harmonic Scalpel for Hepatic Parenchymal Transection in Living Donor Hepatectomy: a Randomized Controlled Trial.
Sultan, A. M., Shehta, A. et al. (2019). J Gastrointest Surg; [record in progress].

Eye Protection in Liver Transplantation Patients Under General Anesthesia.
Yang, S. C., Lee, H. Y. et al. (2018). Transplantation Proceedings 50(9): 2651-2653.

Heart transplantation

A randomized trial comparing triiodothyronine (T3) with thyroxine (T4) for hemodynamically unstable brain-dead organ donors.
Dhar, R., Stahlschmidt, E. et al. (2019). Clinical Transplantation; 33(3).

Lung transplantation

A randomized trial of everolimus-based quadruple therapy versus standard triple therapy early after lung transplantation.
Gottlieb, J., Neurohr, C. et al. (2019). American Journal of Transplantation [record in progress].

Omega-3 fatty acid supplement skin cancer prophylaxis in lung transplant recipients: A randomized, controlled pilot trial.
Miura, K., Vail, A. et al. (2019). Journal of Heart & Lung Transplantation38(1).

Various organs

Assessment of Tacrolimus Intra-patient Variability in Stable Adherent Transplant Recipients: Establishing Baseline Values.
Leino, A. D., King, E. C. et al. (2018). American Journal of Transplantation; [record in progress].