Transplant Trial Watch

To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.

The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].

The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.

Click on each trial for more detail of findings and quality.

November 2018

Kidney transplantation

Fosfomycin trometamol in the prophylaxis of post-kidney transplant urinary tract infection: A controlled, randomized clinical trial.
Arreola-Guerra JM, Rosado-Canto R et al. Transpl Infect Dis. 2018; [record in progress].

Why is transition between child and adult services a dangerous time for young people with chronic kidney disease? A mixed-method systematic review.
Dallimore DJ, Neukirchinger B et al. PLoS ONE [Electronic Resource] 2018; [record in progress].

Effects of marine n-3 fatty acid supplementation in renal transplantation: a randomized controlled trial.
Eide IA, Reinholt FP et al. Am J Transplant. 2018; [record in progress].

Graft Pre-conditioning by Peri-Operative Perfusion of Kidney Allografts With Rabbit Anti-human T-lymphocyte Globulin Results in Improved Kidney Graft Function in the Early Post-transplantation Period-a Prospective, Randomized Placebo-Controlled Trial.
Ritschl PV, Gunther J et al. Front. 2018; 9:1911.

Optimal surgical management in kidney and pancreas transplantation to minimise wound complications: A systematic review and meta-analysis.
Shahrestani S, Tran HM et al. Annals of Medicine & Surgery, 2018; 33: 24-31.

Long-term cardiovascular outcome of renal transplant recipients after early conversion to everolimus compared to calcineurin inhibition: results from the randomized controlled MECANO trial.
van Dijk M, van Roon AM et al. Transpl Int. 2018; [record in progress].

Liver transplantation

Survival following right lobe split graft, living- and deceased-donor liver transplantation in adult patients: a systematic review and network meta-analysis.
Gavriilidis P, Tobias A, et al. Transplant Int. 2018; 31(10): 1071-1082.

Heart transplantation

Induction immunosuppressive therapy in cardiac transplantation: a systematic review and meta-analysis.
Briasoulis A, Inampudi C et al. Heart Failure Reviews, 2018; 23(5): 641-649.

Various organs

A randomized clinical trial of age and genotype-guided tacrolimus dosing after pediatric solid organ transplantation.
Min S, Papaz T et al. Pediatr Transplant. 2018; [record in progress].

The Effect of Reciprocity Priming on Organ Donor Registration Intentions and Behavior.
O'Carroll RE, Quigley J, Miller CB. Ann Behav Med. 2018; [record in progress].