Transplant Trial Watch

To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.

The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].

The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.

Click on each trial for more detail of findings and quality.

November 2021

Kidney transplantation

Marine n-3 Polyunsaturated Fatty Acids and Bone Mineral Density in Kidney Transplant Recipients: A Randomized, Placebo-Controlled Trial.
Jorgensen, H. S., et al Nutrients 2021; 13(7): 10.

A Randomized Controlled Trial of a Pretransplant Educational Intervention in Kidney Patients.
Mansell, H., et al. Transplantation Direct 2021; 7(10): e753.

Immunoguided Discontinuation of Prophylaxis for Cytomegalovirus Disease in Kidney Transplant Recipients Treated with Antithymocyte Globulin: A Randomized Clinical Trial.
Paez-Vega, A., et al. Clinical Infectious Diseases 2021 [record in progress].

Autologous bone marrow-derived mesenchymal stromal cell therapy with early tacrolimus withdrawal: The randomized prospective, single-center, open-label TRITON study.
Reinders, M. E. J., et al. American Journal of Transplantation 2021; 21(9): 3055-3065.

Is simplification of immunosuppressive medication a way to promote medication adherence of kidney transplant recipients? Findings from a randomized controlled trial.
van Zanten, R., et al. Transplant International 2021; 34(9): 1703-1711.

Liver transplantation

Remote Consultations Versus Standard Face-to-Face Appointments for Liver Transplant Patients in Routine Hospital Care: Feasibility Randomized Controlled Trial of myVideoClinic.
Damery, S., et al. Journal of Medical Internet Research 2021; 23(9): e19232.

Steroid pretreatment of deceased donors and liver allograft function - Ten years follow-up of a blinded randomized placebo controlled trial.
Gy├Âri, G. P., et al. International Journal of Surgery 2021; 94: 106095.

Efficacy and safety of basiliximab as initial immunosuppression in liver transplantation: A single center study.
Hashim, M., et al. Annals of Hepatology 2020; 19(5): 541-545.

Lung transplantation

Graphic narrative based informed consent for bronchoscopy improves satisfaction in patients after lung-transplantation: A randomized controlled trial.
Seeliger, B., et al. Patient Education & Counseling 2021 [record in progress].

Various organs

Outcome measures in solid organ donor management research: a systematic review.
Bera, K. D., et al. British Journal of Anaesthesia 2021 [record in progress].