Transplant Trial Watch

To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.

The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].

The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.

Click on each trial for more detail of findings and quality.

September 2019

Kidney transplantation

Use of a Muscle Pump Activator Leads to Improved Lower Limb Edema, Lower Limb Blood Flow, and Urine Output Compared With Standard TED Stockings and Compression Devices Following Kidney Transplant: A Randomized Controlled Trial.
Aquil, S., Alharbi, B. et al. (2019). Transplantation Proceedings; [record in progress].

Prospective randomized study comparing everolimus and mycophenolate sodium in de novo kidney transplant recipients from expanded criteria deceased donor.
Ferreira, A. N., Felipe, C. R. et al. (2019). Transplant International 06: 06.

Improving medication adherence and outcomes in adult kidney transplant patients using a personal systems approach: SystemCHANGETM results of the MAGIC randomized clinical trial.
Russell, C. L., Hathaway, D. et al. (2019). American Journal of Transplantation 10:10.

Antibiotic Treatment Versus No Treatment for Asymptomatic Bacteriuria in Kidney Transplant Recipients: A Multicenter Randomized Trial.
Sabe, N., Oriol, I. et al. (2019). Open Forum Infectious Diseases 6(6):ofz243.

Liver transplantation

Body weight parameters are related to morbidity and mortality after liver transplantation - A systematic review and meta-analysis.
Beckmann, S., et al. (2019). Transplantation 24: 24.

Heart transplantation

Accelerated Allograft Vasculopathy With Rituximab After Cardiac Transplantation.
Starling, R. C., Armstrong, B. et al. (2019). Journal of the American College of Cardiology 74(1): 36-51.

Lung transplantation

Bilateral lung transplantation provides better long-term survival and pulmonary function than single lung transplantation: A systematic review and meta-analysis.
Yu, H., et al. (2019). Transplantation 24:24.

Various organs

Interventions to Prevent Nonmelanoma Skin Cancers in Recipients of a Solid Organ Transplant: Systematic Review of Randomized Controlled Trials.
Chung, E. Y. M., et al. (2019). Transplantation 103(6): 1206-1215.

The Patients Save Lives Program to Facilitate Organ Donor Designation in Primary Care Offices.
Degenholtz, H. B., Creppage, K. et al. (2019). Progress in Transplantation; [record in progress].