To keep the transplantation community informed about recently published evidence in organ transplantation the Centre for Evidence in Transplantation has developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
February 2026
Kidney transplantation
A Two-Center Randomized Controlled Trial to Assess Financial Incentives for Compliance With Living Kidney Donor Follow-Up in the United States.
Bisen, S. S., et al. Clin Transplant. 2025 Dec;39(12):e70401.
The Efficacy and Safety of SGLT2 Inhibitors in Diabetes Kidney Transplant Recipients: A Systematic Review and Meta-Analysis.
Boonpiraks, K., et al. F1000Res. 2025 Mar 25;14:329.
Impact of kidney function on 200 days of antiviral prophylaxis for cytomegalovirus disease in cytomegalovirus-seronegative recipients of cytomegalovirus-seropositive donor kidneys: Post hoc analysis of a randomized, phase 3 trial of letermovir vs valganciclovir prophylaxis.
Budde, K., et al. Am J Transplant. 2025 Dec;25(12):2621-2633.
The impact of immunosuppression withdrawal strategies on sensitization and safety outcomes after kidney transplant failure: A systematic review with meta-analysis.
Fragoso, P., et al. Transplant Rev (Orlando). 2026 Jan;40(1):100982.
One-stop early noninvasive evaluation of renal allograft rejection and fibrosis: microstructural mapping via time-dependent diffusion MRI.
Liao, Z., et al. E Bio Medicine. 2025 Dec;122:106034
Intraoperative unfractionated heparin (UFH) for kidney transplantation: A systematic review and meta-analysis.
Singla, A., et al. Transplant Rev (Orlando). 2026 Jan;40(1):100985.
Heart transplantation
Cardiac Allograft Vasculopathy Inhibition With Alirocumab: The CAVIAR Trial.
Fearon, W. F., et al. Circulation. 2026 Jan 6;153(1):7-17.
Cardiac Allograft Vasculopathy in Heart Transplantation From Circulatory Death Donors: A Systematic Review and Meta-Analysis.
Safdar, W., et al. Clin Transplant. 2026 Jan;40(1):e70435.
Various organs
Association Between Cytomegalovirus Viremia Clearance and Post-Solid Organ Transplant Mortality in Patients With Refractory Cytomegalovirus Infection: SOLSTICE Post Hoc Analysis.
Kamar, N., et al. Transpl Int. 2025 Nov 26;38:15331.
Optimizing the timing of organ procurement from donors after brainstem death: Impact on outcomes in abdominal organ transplantation - A systematic review.
Koliakos N., et al. Transplant Rev (Orlando). 2026 Jan;40(1):100987.

