Transplant Trial Watch

To keep the transplantation community informed about recently published evidence in organ transplantation the Centre for Evidence in Transplantation has developed the Transplant Trial Watch.

The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].

The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.

Click on each trial for more detail of findings and quality.


September 2025

Kidney transplantation

Anterior quadratus lumborum block is superior to erector spinae plane block for analgesia after renal transplantation: a randomized controlled trial.
An, Y., et al. BMC Anesthesiology 2025; 25(1): 343.

The Impact of Thyroid Hormones on Brain-Dead Organ Donors: A Systematic Review and Meta-Analysis.
Cavalcante, L. F. F., et al. Transplantation Proceedings 2025; 57(5): 698-705.

Impact of intraoperative goal-directed therapy on perioperative outcomes in kidney transplantation: a multicenter randomized controlled trial.
Cristiana, L., et al. Internal & Emergency Medicine 2025 [record in progress].

Meta-Analysis and Clinical Guidance of Oxygenated Hypothermic Machine Perfusion for Kidney Transplantation.
Jia, D., et al. Transplantation Proceedings 2025; 57(5): 752-763.

Renal resistance trajectories during hypothermic machine perfusion in kidneys donated after circulatory death: associations with donor characteristics and post-transplant outcomes-an analysis of COMPARE Trial Data.
Verstraeten, L., et al. American Journal of Transplantation 2025 [record in progress]

Liver transplantation

Liver transplantation for primary and secondary liver tumors: Patient-level meta-analyses compared to UNOS conventional indications.
Ciria, R., et al. Hepatology 2025; 81(6): 1700-1713.

Should We Use Behavioural Predictions in Organ Allocation?
Drezga-Kleiminger, M., et al. Bioethics 2025 [record in progress].

Minimally Invasive Donor Hepatectomy in Living Donor Liver Transplantation-Evidence of Benefit?: A Systematic Review and Meta-analysis of Current Literature.
Giglio, M. C., et al. Transplantation 2025 [record in progress].

Postoperative Outcomes Following Liver Transplantation for Wilson's Disease: A Systematic Review and Meta-Analysis.
Wang, A., et al. Clinical Transplantation 2025; 39(6): e70155.

Lung transplantation

Allogeneic mesenchymal stromal cell therapy on primary graft dysfunction after lung transplantation.
Qayyum, A. A., et al. JHLT Open 2025; 8: 100254.