Transplant Trial Watch

To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.

The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].

The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.

Click on each trial for more detail of findings and quality.

August 2020

Kidney transplantation

A randomised, controlled trial comparing the immunogenecity and safety of a 23-valent pneumococcal polysaccharide vaccination to a repeated dose 13-valent pneumococcal conjugate vaccination in kidney transplant recipients.
Eriksson, M., et al. Transplant Infectious Disease 2020 [record in progress]

ICT-based adherence monitoring in kidney transplant recipients: a randomized controlled trial.
Jung, H. Y., et al. BMC Medical Informatics & Decision Making 2020; 20(1): 105.

Physical activity and risk of cardiovascular events and all-cause mortality among kidney transplant recipients.
Kang, A. W., et al. Nephrology Dialysis Transplantation 2020 [record in progress]

Preliminary Assessment of Safety and Adherence to a Once Daily Immunosuppression Regimen in Kidney Transplantation: Results of a Randomized Controlled Pilot Study.
Taber, D. J., et al. Clinical Transplantation 2020: e13844.

Three-year outcomes from the CRADLE study in de novo pediatric kidney transplant recipients receiving everolimus with reduced tacrolimus and early steroid withdrawal.
Tonshoff, B., et al. American Journal of Transplantation 2020 [record in progress].

Liver transplantation

Use of machine perfusion in livers showing steatosis prior to transplantation: a systematic review.
Lai, Q., et al. Updates in Surgery 2020 [record in progress]

Heart transplantation

Long-term effects of high-intensity training vs. moderate intensity training in heart transplant recipients: A 3-year follow-up study of the randomized controlled HITTS study
Rolid, K., et al. American Journal of Transplantation 2020 [record in progress]

Lung transplantation

Usefulness of gene expression profiling of bronchoalveolar lavage cells in acute lung allograft rejection.
Weigt, S. S., et al. Journal of Heart & Lung Transplantation 2019; 38(8): 845-855.

Felodipine and renal function in lung transplantation: A randomized placebo-controlled trial.
Hornum, M., et al. Journal of Heart & Lung Transplantation 2020; 39(6): 541-550.