To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
September 2023
Kidney transplantation
Urine CXCL10 to Assess BK Polyomavirus Replication After Kidney Transplantation.
Haller, J., et al. Transplantation 2023 [record in progress].
Balanced crystalloid solution versus saline in deceased donor kidney transplantation (BEST-Fluids): a pragmatic, double-blind, randomised, controlled trial.
Collins, M. G., et al. Lancet 2023; 402(10396): 105-117.
Social network interventions to reduce race disparities in living kidney donation: Design and rationale of the friends and family of kidney transplant patients study (FFKTPS).
Daw, J., et al. Clinical Transplantation 2023 [record in progress].
Comparison of Bipolar vascular sealing and conventional back-table dissection in terms of post-renal transplant drainage and back-table preparation times.
Eren, E., et al. European Review for Medical & Pharmacological Sciences 2023; 27(13): 6223-6228.
Kidney Transplantation From Donors With Acute Kidney Injury: Are the Concerns Justified? A Systematic Review and Meta-Analysis.
Nita, G. E., et al. Transplant International 2023; 36: 11232.
A Randomized Controlled Trial of Envarsus Versus Immediate Release Tacrolimus in Kidney Transplant Recipients With Delayed Graft Function.
Parajuli, S., et al. Transplantation Proceedings 2023 [record in progress].
The role of flavin mononucleotide (FMN) as a potentially clinically relevant biomarker to predict the quality of kidney grafts during hypothermic (oxygenated) machine perfusion.
van de Leemkolk, F. E. M., et al. PLoS ONE [Electronic Resource] 2023; 18(6): e0287713.
Liver transplantation
Normothermic Machine Perfusion of Donor Livers for Transplantation in the United States - A Randomized Controlled Trial.
Chapman, W. C., et al Annals of Surgery 2023 [record in progress]
End-ischemic hypothermic oxygenated perfusion for extended criteria donors in liver transplantation: a multicenter, randomized controlled trial-HOPExt.
Pradat, P., et al. Trials [Electronic Resource] 2023; 24(1): 379.
A randomized, controlled, prehabilitation intervention to maximize early recovery (PRIMER) in liver transplantation.
Serper, M., et al. Liver Transplantation 2023 [record in progress].