Transplant Trial Watch

To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.

The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].

The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.

Click on each trial for more detail of findings and quality.

February 2019

Kidney transplantation

Comparison of Three-Quadrant Transversus Abdominis Plane Block and Continuous Epidural Block for Postoperative Analgesia After Transperitoneal Laparoscopic Nephrectomy.
Aditianingsih D, Mochtar CA, et al. Anesth. 2018; 8(5):e80024.

Outcome of Sirolimus based Immunosuppression, Fifteen Years Post Live-Donor Kidney Transplantation: Single Center Experience.
Hamdy AF, Elhadedy MA, et al. Clin Transplant. 2018; [record in progress].

Urinary Markers of Fibrosis and Risk of Cardiovascular Events and Death in Kidney Transplant Recipients: The FAVORIT Trial.
Park M, Katz R, et al. Am J Transplant. 2017; 17(10):2640-9.

Effects of the strict control of blood pressure in pediatric renal transplant recipients-ESCORT trial.
Seeman T, Vondrak K, Dusek J. Pediatr Transplant. 2018; [record in progress].

Liver transplantation

Pilot, open, randomized, prospective trial for normothermic machine perfusion evaluation in liver transplantation from older brain death donors.
Ghinolfi D, Rreka E, et al. Liver Transpl. 2018; [record in progress].

Hyperglycemia in the Posttransplant Period: NODAT vs Posttransplant Diabetes Mellitus.
Gupta S, Pollack T, et al. Journal of the Endocrine Society. 2018; 2(11):1314-9.

Combined Flush With Histidine-Tryptophan-Ketoglutarate and University of Wisconsin Solutions in Liver Transplantation: Preliminary Results.
Leon Diaz FJ, Fernandez Aguilar JL, et al. Transplantation Proceedings. 2018; 50(2):539-42.

Association Between Renal Dysfunction and Major Adverse Cardiac Events After Liver Transplantation: Evidence from an International Randomized Trial of Everolimus-Based Immunosuppression.
Saliba F, Fischer L, et al. Ann Transplant. 2018; 23:751-7.

Outcomes of immunosuppression minimization and withdrawal early after liver transplantation.
Shaked A, DesMarais MR, et al. Am J Transplant. 2018; [record in progress].

Various organs

Prophylaxis of human toxoplasmosis: a systematic review.
Rajapakse S, Weeratunga P, et al. Pathog Glob Health. 2017; 111(7):333-42.