About Us

Liset Pengel

Liset Pengel

Chief Executive Officer and Co-Director

[email protected]

Liset received her PhD from the faculty of Health Sciences at the University of Sydney (Australia) in 2003. She has worked at the Centre for Evidence in Transplantation (CET) since 2005, when it was founded by Sir Peter Morris. She has conducted and co-authored systematic reviews and is actively involved in the CET Network, which is a network of transplant centres who have an interest in conducting high quality systematic reviews.

Liset has developed the Transplant Library from inception to be the definitive resource of high-quality evidence on all aspects of solid organ transplantation. The Library has been formally endorsed by leading transplantation societies around the world. The Transplant Evidence app (released in 2021) makes some of the content easily accessible.

Liset is also a councillor of the European Society for Organ Transplantation (ESOT), board member of ESOT’s Education Committee and course lead of ESOT’s ACADEMIA course. As part of ESOT’s partnership with CET she provides expert advice to ESOT members regarding systematic reviews, trial design and the development of guidelines and consensus statements.

Publications

Bellini MI, Nozdrin M, Pengel L, Knight S, Papalois V. Risks for donors associated with living kidney donation: meta-analysis. Br J Surg. 2022;109(8):671-678 [PMID:35612960]

De Smet S, O'Donoghue K, Lormans M, Monbaliu D, Pengel L. Does Exercise Training Improve Physical Fitness and Health in Adult Liver Transplant Recipients? A Systematic Review and Meta-analysis. Transplantation [published online] [PMID:36192838]

Mamode N, Bestard O, Claas F, Furian L, Griffin S, Legendre C, Pengel L, Naesens M. European Guideline for the Management of Kidney Transplant Patients With HLA Antibodies: By the European Society for Organ Transplantation Working Group. Transpl Int. 2022;35:10511 [PMID:36033645]

Naesens M, Schneeberger S; ESOT Working Group. Redefining Risk Stratification and Endpoints for Clinical Trials in Kidney Transplantation: Rationale and Methodology of Proposals Submitted to the European Medicines Agency by the European Society for Organ Transplantation. Transpl Int. 2022;35:10142. [PMID:35992750]

Naesens M, Loupy A, Hilbrands L, Oberbauer R, Bellini MI, Glotz D, Grinyó J, Heemann U, Jochmans I, Pengel L, Reinders M, Schneeberger S, Budde K. Rationale for Surrogate Endpoints and Conditional Marketing Authorization of New Therapies for Kidney Transplantation. Transpl Int. 2022;35:10137 [PMID:35669977]

Hilbrands L, Budde K, Bellini MI, Diekmann F, Furian L, Grinyó J, Heemann U, Hesselink DA, Loupy A, Oberbauer R, Pengel L, Reinders M, Schneeberger S, Naesens M. Allograft Function as Endpoint for Clinical Trials in Kidney Transplantation. Transpl Int. 2022;35:10139 [PMID:35669976]

Seron D, Rabant M, Becker JU, Roufosse C, Bellini MI, Böhmig GA, Budde K, Diekmann F, Glotz D, Hilbrands L, Loupy A, Oberbauer R, Pengel L, Schneeberger S, Naesens M. Proposed Definitions of T Cell-Mediated Rejection and Tubulointerstitial Inflammation as Clinical Trial Endpoints in Kidney Transplantation. Transpl Int. 2022;35:10135 [PMID:35669975]

Naesens M, Budde K, Hilbrands L, Oberbauer R, Bellini MI, Glotz D, Grinyó J, Heemann U, Jochmans I, Pengel L, Reinders M, Schneeberger S, Loupy A. Surrogate Endpoints for Late Kidney Transplantation Failure. Transpl Int. 2022;35:10136 [PMID:35669974]

Roufosse C, Becker JU, Rabant M, Seron D, Bellini MI, Böhmig GA, Budde K, Diekmann F, Glotz D, Hilbrands L, Loupy A, Oberbauer R, Pengel L, Schneeberger S, Naesens M. Proposed Definitions of Antibody-Mediated Rejection for Use as a Clinical Trial Endpoint in Kidney Transplantation. Transpl Int. 2022;35:10140 [PMID:35669973]

Bestard O, Thaunat O, Bellini MI, Böhmig GA, Budde K, Claas F, Couzi L, Furian L, Heemann U, Mamode N, Oberbauer R, Pengel L, Schneeberger S, Naesens M. Alloimmune Risk Stratification for Kidney Transplant Rejection. Transpl Int. 2022;35:10138 [PMID:35669972]

Tong A, Oberbauer R, Bellini MI, Budde K, Caskey FJ, Dobbels F, Pengel L, Rostaing L, Schneeberger S, Naesens M. Patient-Reported Outcomes as Endpoints in Clinical Trials of Kidney Transplantation Interventions. Transpl Int. 2022;35:10134. [PMID:35669971]

Rana Magar R, Knight S, Stojanovic J, Marks SD, Lafranca JA, Turner S, Dor FJMF, Pengel LHM. Is Preemptive Kidney Transplantation Associated With Improved Outcomes when Compared to Non-preemptive Kidney Transplantation in Children? A Systematic Review and Meta-Analysis. Transpl Int. 2022;35:10315 [PMID:35368639]

Bellini MI, Nozdrin M, Pengel L, Knight S, Papalois V. How good is a living donor? Systematic review and meta-analysis of the effect of donor demographics on post kidney transplant outcomes. J Nephrol. 2022;35(3):807-820. [PMID:35072936]

Bellini MI, Nozdrin M, Pengel L, Knight S, Papalois V. The Impact of Recipient Demographics on Outcomes from Living Donor Kidneys: Systematic Review and Meta-Analysis. J Clin Med. 2021;10(23):5556 [PMID:34884257]

Jochmans I, Hessheimer AJ, Neyrinck AP, Paredes D, Bellini MI, Dark JH, Kimenai HJAN, Pengel LHM, Watson CJE; ESOT Workstream 04 of the TLJ (Transplant Learning Journey) project. Consensus statement on normothermic regional perfusion in donation after circulatory death: report from the European Society for Organ Transplantation's Transplant Learning Journey. Transplant International 2021 [record in progress] [PMID:34145644]

Bellini MI, Pengel L, Potena L, Segantini L; ESOT COVID-19 Working Group. COVID-19 and education: restructuring after the pandemic. Transplant International 2021; 34(2):220-223 [PMID:33205410]

Masnou N, Bellini MI, Pengel LHM, Feltrin G; TLJ 2.0 Working Group Expanding the Donor Pool. It is not only extending donor criteria: it is extending the donor pool. A cross-sectional survey from the European Society of Organ Transplantation. Transplant International 2021; 34(4): 754-755 [PMID:33529375]

De Beule J, Vandendriessche K, Pengel LHM, Bellini MI, Dark JH, Hessheimer AJ, Kimenai HJAN, Knight SR, Neyrinck AP, Paredes D, Watson CJE, Rega F, Jochmans I. A systematic review and meta-analyses of regional perfusion in donation after circulatory death solid organ transplantation. Transplant International 2021 [record in progress] [PMID:34570380]

Hellemans R, Pengel LHM, Choquet S, Maggiore U; for ESOT Workstream 3 of the TLJ (Transplant Learning Journey) project. Managing immunosuppressive therapy in potentially cured post-kidney transplant cancer (excluding non-melanoma skin cancer): an overview of the available evidence and guidance for shared decision-making. Transplant International 2021;34(10): 1789-1800 [PMID:34146426]

O'Donoghue KJM, Pengel LHM, Ayaz-Shah AA, Knight SR. Do the Online Materials Provided by United Kingdom Renal Transplant Centres Adequately Answer Questions asked by Transplant Recipients, Patients on the Transplant Waiting List, Carers and Live Kidney Donors? (Poster presentation at the TTS Congress, Madrid, Spain, 1-5 July, 2018).

OʼDonoghue KJM, Reed RD, Knight SR, O'Callaghan JM, Ayaz-Shah AA, Hassan S, Weissenbacher A, Morris PJ, Pengel LHM. Critical Appraisal of International Clinical Practice Guidelines in Kidney Transplantation Using the Appraisal of Guidelines for Research and Education (AGREE) II Tool: A Systematic Review. Transplantation 2018; 102(9):1419-1439. [PMID:29787524]

Sneiders D, Houwen T, Pengel LHM, Polak WG, Dor FJMF, Hartog H. Systematic review and meta-analysis of posttransplant hepatic artery and biliary complications in patients treated with transarterial chemoembolization before liver transplantation. Transplantation. 2018; 102 (1): 88-96. [PMID:28885493]

O’Donoghue KJM, Reed RD, Knight SR, O’Callaghan JM, Ayaz-Shah AA, Hassan S, Morris PJ, Pengel LHM. Systematic review of clinical practice guidelines in kidney transplantation. BJS Open 2017; 1(4): 97–105. [PMID:29951611]

O'Donoghue KJM, Reed RD, Knight SR, O'Callaghan JM, Ayaz-Shah AA, Hassan S, Weißenbacher A, Morris PJM, Locke J, Pengel LHM. Critical appraisal of international clinical practice guidelines in kidney transplantation using the Appraisal of Guidelines for Research and Education (AGREE) II tool: A systematic review. 2017 (Accepted Abstract at the BTS Congress, Yorkshire, UK, 1-3 March, 2017).

O'Callaghan JM, Pall KT, Pengel L, Consortium for Organ preservation in Europe (COPE). Supplemental oxygen during hypothermic kidney preservation: A systematic review. Transplant Rev (Orlando). 2017; 31(3): 172-179. [PMID:28259374]

Jochmans I, Akhtar MZ, Nasralla D, Kocabayoglu P, Boffa C, Kaisar M, Brat A, O'Callaghan J, Pengel LH, Knight S, Ploeg R. Past, present and future of dynamic kidney and liver preservation and resuscitation. Am J Transplant. 2016; 16(9):2545-55. [PMID:26946212]

O'Donoghue KJM, Reed RD, Knight SR, O'Callaghan JM, Morris PJ, Locke J, Pengel LHM. Critical Appraisal of Clinical Practice Guidelines in Kidney Transplantation using the Appraisal of Guidelines for Research and Education (AGREE) II tool: A Systematic Review. 2016. (Poster presentation at the BTS Congress, Glasgow, UK, 24-26 February, 2016).

Knight SR, Morris PJ, Schneeberger S, Pengel LH. Trial design and end points in clinical transplant research. Transpl Int. 2016;29(8):870-9 [PMID:26749215]

Talawila N, Pengel LH. Does belatacept improve outcomes for kidney transplant recipients? A systematic review. Transpl Int. 2015; 28(11):1251–1264 [PMID:25965549]

Pengel LHM, Pall K, O'Callaghan J. Hypothermic Versus Normothermic In Situ Regional Perfusion Using The Extracorporeal Membrane Oxygenation (ECMO) Technique In Donation After Circulatory Death (DCD) In Kidney And Liver Transplantation: A Systematic Review [0216]. (Poster presentation at the joint BTS/NTV Congress, Bournemouth, UK, 11-13 March, 2015).

Schnitzbauer AA, Proneth A, Pengel L, Ansorg J, Anthuber M, Bechstein WO, Schlitt HJ, Geissler EK. Evidence-Based Medicine in Daily Surgical Decision Making: A Survey-Based Comparison between the UK and Germany. European Surgical Research. Oct 9 2014; 54(1-2):14-23. [PMID:25322938]

Pall K, Pengel L, O'Callaghan J. What is the evidence for oxygenated hypothermic preservation in kidney transplantation? A systematic Review. (Poster presentation at the World Transplant Congress, San Francisco, 2014)

Talawila N, Pengel LHM. Does Belatacept Improve Outcomes For Kidney Transplant Recipients? A Systematic Review of Randomised Controlled Trials (Poster presentation at the British Transplantation Society Congress, Glasgow, March 2014)

Pengel LHM, Knight SK, Morris PJ. Transplant Library - the definitive resource of high quality evidence in solid organ. RCS Annual Day 2014 and SITU’s Launch, March 26, 2014, University of Oxford, UK.

Pengel L, Knight S, Emin A, O'Callaghan J, Van der Meulen J, Papalois V, Morris P. How to teach evidence-based practice skills in 1.5 days: The Evidence in Transplantation (EVIT) Course. (Poster presentation at the European Society for Organ Transplantation, Vienna 2013)

Pengel LHM, Knight S, Emin A, O'Callaghan J, Van der Meulen J, Papalois V, Morris P. How to teach evidence-based practice skills in 1.5 days: the Evidence in Transplantation (EVIT) course. Transplant International. 2013; 26(Supp s2);192

Knight SR, Pengel LHM, Morris PJ. Chapter 42: Evidence in Transplantation in Kidney Transplantation: Principles and Practice. 7th edition. Eds. P. J. Morris and Stuart J Knechtle, Elsevier, Philadelphia. p729- 736

Pengel LHM, Morris PJ. Transplant Library - the definitive resource of high quality evidence in solid organ. Evidence Live, March 25-26, 2013, University of Oxford, UK.

Pengel LHM, Knight S, Emin A, O’Callaghan J, Van der Meulen J, Papalois V, Morris PJ. How to teach evidence-based skills in 1.5 days: the Evidence in Transplantation (EVIT) Course. 16th Congress of the European Society for Organ Transplantation, September 8-11, 2013, Vienna, Austria

Liu, LQ, Morris PJ, et al. Compliance to the CONSORT statement of randomized controlled trials in solid organ transplantation: a 3-year overview. Transplant International 2013; 26(3): 300-306. [PMID:23279054]

Liu LQ*, Pengel L and Morris PJ. Do Reports Of Randomised Controlled Trials In Solid Organ Transplantation Adhere To The 2010 CONSORT Statement? A 3-year Overview. 15th Annual Congress of the British Transplantation Society in Glasgow, 22nd-24th Feb, 2012. * presenting author

Zucker K, Pengel LH*, Liu LQ, Morris PJ. The Rate of Publication of Abstracts in Solid Organ Transplantation Presented at Scientific Meetings. 24th International Congress of The Transplantation Society, July 15 - 19, 2012, Berlin, Germany. * presenting author

Pengel L, Morris P. The Transplant Library of randomized controlled trials and systematic reviews. Transplantation 2011; 92(6):613-6 [PMID:21866077]

Pengel LHM, Liu LQ, Morris PJ. Do wound complications or lymphoceles occur more often in solid organ transplant recipients on mTOR inhibitors? A systematic review of randomized controlled trials. Transplant International 2011; 24(12):1216-1230 [PMID:21955006]

Liu LQ*, Pengel L and Morris PJ. Reporting of quality of randomised controlled trials in solid organ transplantation. ESOT Congress. Glasgow, 4-7th September 2011. * presenting author

Pengel L, Barcena L and Morris PJ. Quality of reporting of randomised controlled trials in organ transplantation. Transplant International 2009; 22(4):377-84 [PMID:19000234]

Refshauge KM, Raymond J, Kilbreath SL, Pengel L and Heijnen I. The effect of ankle taping on detection of inversion-eversion movements in participants with recurrent ankle sprain. American Journal of Sports Medicine 2009; 37(2):371-5 [PMID:18927252]

Barcena L, Pengel L and Morris PJ. Searching the transplantation library. Transplantation. 2008 Apr 27;85(8):1068-74. [PMID:18431222]

Pengel L, Barcena L, Morris PJ*. Quality of reporting of randomized controlled trials in solid organ transplantation. 22nd Congress of the Transplantation Society, August 10 -14, 2008, Sydney, Australia. * presenting author

Pengel LH, Refshauge KM, Maher CG, Nicholas MK, Herbert RD and McNair P. Physiotherapist-directed exercise, advice, or both for subacute low back pain: a randomized trial. Annals of Internal Medicine 2007; 146(11):787-96 [PMID:17548410]

Pengel L, Barcena L and Morris PJ. Registry of randomized controlled trials in transplant ation: January 1 to June 30, 2006. Transplantation 2007; 83(8): 1001-14 [PMID:17452884]

Hodges PW, Sapsford R and Pengel LH. Postural and respiratory functions of the pelvic floor muscles. Neurourology and Urodynamics 2007;26(3):362-71 [PMID:17304528]

Pengel L, Barcena L and Morris PJ. Registry of Randomized Controlled Trials in Transplantation: January 1 to June 30, 2005 . Transplantation 2006; 81(8):1071-1086 [PMID:16641590]

Pengel L, Barcena L and Morris PJ. Registry of Randomized Controlled Trials in Transplantation: July 1 to December 31, 2005. Transplantation 2006; 82(10):1247-1260 [PMID:17130770]

Pengel L, Barcena L, Morris PJ (2007). Registry of randomized controlled trials in transplantation: July 1 to December 31, 2006. Transplantation 84 (8): 940-953 [PMID:17989595]

Barcena L, Pengel LHM*, Morris PJ. The quality of randomized trials in organ transplantation must be improved. Transplantation 82(1 suppl3): 467-468. World Transplant Congress, July 22 - 27, 2006, Boston, USA. * presenting author

Pengel L, Barcena L, Morris PJ . Registry of randomized controlled trials in transplantation Transplantation 2005; 80(4):432 [PMID:16123713]

Barcena L, Pengel L and Morris PJ . Registry of Randomized Controlled Trials in Transplantation. Transplantation 2005; 80(11):1525-1527 [PMID:16371918]

Pengel LH, Refshauge KM and Maher CG. Responsiveness of pain, disability, and physical impairment outcomes in patients with low back pain. Spine 2004; 29(8):879-83 [PMID:15082988]

Pengel LH, Herbert RD, Maher CG and Refshauge KM. Acute low back pain: systematic review of its prognosis. BMJ 2003; 327(7410):323 [PMID:12907487]

Hodges PW, Pengel LH, Herbert RD and Gandevia SC. Measurement of muscle contraction with ultrasound imaging. Muscle and Nerve 2003; 27(6):682-92 [PMID:12766979]

Pengel HM, Maher CG and Refshauge KM. Systematic review of conservative interventions for subacute low back pain. Clinical Rehabilitation 2002; 16(8):811-20 [PMID:12501942]