A new formula for calculating standard liver volume for living donor liver transplantation without using body weight.
Kokudo T, Hasegawa K, et al.Journal of Hepatology 2015; 63(4): 848-854.
Aims
To report a new formula for calculating the standard liver volume (SLV) that does not use body weight in living donor liver transplantation (LDLT).
Interventions
Non body weight-related variables were used to develop a new formula for LDLT and the accuracy of this formula was tested on a validation sample.
Participants
180 Japanese donor candidates and 160 Swiss patients with normal livers aged 20-65 years
Outcomes
Measured outcomes were age, thoracic width, race, liver volume, body surface area, body mass index, estimated SLV and kidney volume.
Follow-up
3-4 months after transplantation
CET Conclusions
This manuscript reports a new formula for estimating the standard liver volume (SLV) in living donor liver transplantation. The formula uses thoracic width in place of body weight or body surface area, and the authors report better prediction of SLV using this formula compared to previously published formulae. There are some caveats. The model was derived from a population of 180 Japanese donors and 160 Swiss patients undergoing imaging for non-hepatic pathology. This latter group may not be representative of a typical donor population. Validation was performed retrospectively in a small group of 50 Japanese live-donor transplant recipients. Before the formula can be recommended for widespread use, it will need prospective validation in other patient cohorts.
Quality notes
Quality Assessment not appropriate
Trial registration
None