Transplant Trial Watch

Educational Animations to Inform Transplant Candidates About Deceased Donor Kidney Options: An Efficacy Randomized Trial.

Kayler, L. K., et al.

Transplantation Direct 2020; 6(7): e575.

This study aimed to investigate the efficacy of two animations about kidney donor profile index (KDPI) and increased risk donor (IRD) among renal transplant candidates and their caregivers: simplifyKDPI and IRD-1-2-3.

Patients were randomized to either animation viewing and nurse discussion (intervention group) or standard nurse discussion alone (control group).

80 renal transplant candidates (along with 64 caregivers).

The primary outcomes included KDPI and IRD knowledge, and willingness to either receive or encourage to receive an IRD or KDPI> 85% kidney. The secondary outcomes included decisional self-efficacy and animation acceptability.

Immediately following the animation intervention

CET Conclusions
This interesting pilot randomised controlled trial allocated kidney transplant recipients to animations about the kidney donor profile index (KDPI) and increased risk donor (IRD) kidneys plus nurse education versus nurse education alone. Eighty patients were randomised according to a randomisation scheme with sealed envelopes. The post-test survey followed immediately after the intervention and assessed knowledge, decision-making self-efficacy and willingness to accept a hypothetical high KDPI or IRD offer. Clinical staff were blinded to group allocation. The animation intervention improved knowledge scores and willingness to accept an IRD kidney, even after adjusting for confounders. The patients rated the animations highly acceptable. Using animations may be a simple, feasible and helpful tool for patients to understand important concepts related to their health.

Jadad score

Data analysis
Per protocol analysis

Allocation concealment

Trial registration

Funding source
No funding received