To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.
The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].
The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.
Click on each trial for more detail of findings and quality.
November 2013
Kidney transplantation
OSAKA Trial: A randomized, controlled trial comparing tacrolimus QD and BD in kidney transplantation.
Albano L, Banas B, et al. Transplantation 2013;96(10):897-903
Impact of calcineurin-inhibitor conversion to mTOR inhibitor on renal allograft function in a prednisone-free regimen.
Chhabra D, Alvarado A, et al. American Journal of Transplantation 2013;13(11):2902-11
The short-term impact of protocol biopsies in a live-related renal transplant program using tacrolimus based immunosuppression.
Guleria S, Jain S, et al. Indian Journal of Nephrology 2013; 23(4): 253-258.
The renin-aldosterone axis in kidney transplant recipients and its association with allograft function and structure.
Issa N,Ortiz F, et al. Kidney International 2014;85(2):404-15
Mobile health medication adherence and blood pressure control in renal transplant recipients: A proof-of-concept randomized controlled trial.
McGillicuddy JW, Gregoski MJ, et al. JMIR Research Protocols 2013; 2(2): e32.
Critical analysis of valganciclovir dosing and renal function on the development of cytomegalovirus infection in kidney transplantation.
Posadas Salas MA, Taber DJ, et al. Transplant Infectious Disease 2013;15(6):551-8
Low-pressure pneumoperitoneum during laparoscopic donor nephrectomy to optimize live donors' comfort.
Warle MC, Berkers AW, et al. Clinical Transplantation 2013;27(4):E478-83
One-year results of a prospective, randomized trial comparing two machine perfusion devices used for kidney preservation.
Wszola M, Kwiatkowski A, et al. Transplant International 2013;26(11):1088-96
Divided dosing reduces prednisolone-induced hyperglycaemia and glycaemic variability: a randomized trial after kidney transplantation.
Yates CJ, Fourlanos S, et al. Nephrology Dialysis Transplantation 2014; 29(3):698-705
Heart transplantation
Inhaled nitric oxide versus sodium nitroprusside for preoperative evaluation of pulmonary hypertension in heart transplant candidates.
Pasero D, Rana NK, et al. Transplantation Proceedings 45(7): 2746-2749