Combined resistance and endurance training at a moderate-high intensity improves physical condition and quality of life in liver transplant patients.
Moya-Najera D, Moya-Herraiz A, et al.Liver Transplantation 2017; 27: 27.
Aims
To evaluate the effects of a concurrent moderate to high intensity combined resistance-endurance training program in liver transplantation (LT) patients.
Interventions
Participants were randomised to either follow the usual care recommendations (control group), or receive two 75-minute training sessions per week consisting of resistance and aerobic training organized with a circuit distribution, conducted in the hospital and supervised by a qualified health personnel multidisciplinary group which included a sport science professional as a trainer (intervention group).
Participants
54 LT recipients aged between 18-67 years.
Outcomes
The primary outcomes measured were aerobic capacity, maximal strength, body composition, liver function, and health related quality of life.
Follow-up
12 months
CET Conclusions
This study included patients 6 months after liver transplant; they were randomised to standard care or a supervised moderate-high intensity physical training programme including resistance and aerobic exercises. In terms of equipment, only elastic exercise bands and an open space were required. Whilst the study was small (54 patients) the results clearly showed an improvement in the primary outcomes after 24 weeks of the exercise programme. There was a bigger increase in aerobic capacity, maximal strength and health-related quality of life scales. There were no significant changes in body composition or serum tests of liver function. There was a very high level of adherence to the programme (94%). This was probably aided by the exercises taking place on site, under supervision. The method of randomisation was not described, and whilst all patients completed follow up, a significant number of potential patients declined to be included. This was largely due to living too far from the hospital. Achieving similar results at home, without supervision, remains a barrier to using this therapy for all transplant recipients.
Data analysis
Available case analysis
Trial registration
None