News

March 2016 Transplant Trial Watch now available

By: Simon Knight | Posted on 1st March 2016

The March edition of the Transplant Trial Watch is now available via our website and the Trial Watch App. This month’s trials include the effect of Omega-3 on hepatic regeneration after live liver donation, prophylactic azithromycin after lung transplantation, and the consequences of complete tacrolimus withdrawal in renal transplant recipients.

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SONG-TX – developing a core outcome set for renal transplantation

By: Simon Knight | Posted on 17th February 2016

Many clinical trials have been conducted in kidney transplantation but a wide variety of different outcomes are reported and in different ways, and it is unclear whether they are important to people who have received a kidney transplant. There has been no agreement about what are the most important outcomes to measure and report in […]

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Placebo controls in surgical trials

By: Simon Knight | Posted on 2nd February 2016

There is an excellent article in this month’s Bulletin of the Royal College of Surgeons of England about the use of placebo surgery in clinical trials of surgical interventions. The article discusses many of the practical and ethical issues around the use of placebo procedures, including when they should and should not be considered. Interestingly, […]

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February 2016 Transplant Trial Watch now online

By: Simon Knight | Posted on 2nd February 2016

The February 2016 edition of the Transplant Trial Watch is now available. This month’s ten new trials include a comparison of parathyroidectomy and cinacalcet for management of post-transplant hyperparathyroidism, heamoxygenase-1 upregulation in renal transplant recipients and sirolimus for liver transplant recipients with hepatocellular carcinoma.

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January 2016 Transplant Trial Watch now available

By: Simon Knight | Posted on 6th January 2016

The CET team would like to wish everyone a Happy New Year! A new year means that this month’s Transplant Trial Watch is now out. New studies include a systematic review of outcomes in obese kidney transplant recipients, CNI and steroid-free immunosuppression in renal transplantation, and a direct mail campaign to improve donor registration.

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December 2015 Transplant Trial watch now available

By: Simon Knight | Posted on 2nd December 2015

The December 2015 edition of the Transplant Trial Watch is now available online. This month’s trials include the first RCT of robotic donor nephrectomy, Belatacept in Liver Transplantation and tPA for DCD kidney donors. Why not download our app for iPhone, iPad and Android?

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Time of extraction of deceased donor kidneys influences DGF

By: Peter Morris | Posted on 8th October 2015

In a very interesting study with a novel observation, which is in press in the AJT, the authors present an analysis of the impact of the extraction time of kidney (the time from beginning of surgery with aortic cross clamping and perfusion/cooling of the kidneys to removal of kidneys and placing them in ice on the back table). […]

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Mild cooling of organ donor reduces incidence of DGF

By: Peter Morris | Posted on 8th October 2015

This is a fascinating study with significant implications for preservation studies. The authors show that organ donors after brain death subjected to mild cooling had significantly less DGF than donors subjected to conventional normothermia before organ retrieval. In fact the DMC stopped the study on the basis that efficacy had been demonstrated before completion of […]

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October 2015 Transplant Trial Watch now available

By: Simon Knight | Posted on 2nd October 2015

The October 2015 edition of the Transplant Trial watch is now available online and via the Trial Watch app. This month, new studies include long-term outcomes of sirolimus-based immunosuppression in renal transplant recipients, remote ischaemic preconditioning and therapeutic hypothermia in organ donors.

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