Transplant Trial Watch

To keep the transplantation community informed about recently published level 1 evidence in organ transplantation ESOT and the Centre for Evidence in Transplantation have developed the Transplant Trial Watch.

The Transplant Trial Watch is a monthly overview of 10 new randomised controlled trials (RCTs) and systematic reviews. It includes a brief description of each study, an assessment of the reporting of some methodological quality features and the main conclusions of the report written by the Centre for Evidence in Transplantation (CET). RCTs and systematic reviews are selected by the Centre for Evidence in Transplantation on the basis of quality or interest. Electronic publications ahead of print are listed as [record in progress].

The first issue of the Transplant Trial Watch was published in September 2009. It is now made available to thousands of transplant professionals worldwide each month.

Click on each trial for more detail of findings and quality.

July 2014

Kidney transplantation

Antibiotic prophylaxis for preventing post solid organ transplant tuberculosis.
Adamu B, Abdu A, et al. Cochrane Database of Systematic Reviews 3: CD008597 2014

Treatment of hepatitis C after kidney transplant: A pooled analysis of observational studies.
Fabrizi F, Penatti A, et al. Journal of Medical Virology 2014 86(6): 933-940

The effect of remote ischemic post-conditioning on graft function in patients undergoing living donor kidney transplantation.
Kim WH, Lee JH, Kim GS, et al. Transplantation; 98(5): 529-536

Benefits of rituximab combined with intravenous immunoglobulin for desensitization in kidney transplant recipients.
Vo AA, Choi J, Cisneros K, et al. Transplantation 2014; 98(3): 312-319

Liver transplantation

Methods of preventing bacterial sepsis and wound complications after liver transplantation.
Gurusamy K, Nagendran SM, et al. Update of Cochrane Database Syst Rev. 2008;(4) PMID: 18843724.Cochrane Database of Systematic Reviews 3: CD006660 2014.

Prospective randomized pilot study of Y90 +/- sorafenib as bridge to transplantation in hepatocellular carcinoma.
Kulik L, Vouche M, Koppe S, et al. Journal of hepatology 2014; 61 (2): 309-317

Gastrointestinal side effects in liver transplant recipients taking enteric-coated mycophenolate sodium vs. mycophenolate mofetil.
Lopez-Solis R, Devera M, Steel J, et al. Clinical transplantation [record in progress].

Heart transplantation

Thyroid hormone signalling is altered in response to physical training in patients with end-stage heart failure and mechanical assist devices: potential physiological consequences?
Adamopoulos S, Gouziouta A, Mantzouratou P, et al. Interact Cardiovasc Thorac Surg. 2013;17(4):664-8.

Lung transplantation

A randomized trial of the effects of nebulized albuterol on pulmonary edema in brain-dead organ donors.
Ware LB, Landeck M, Koyama T, et al. Am J Transplant. 2014;14(3):621-8.


Effects of an education program on intensive care unit nurses' attitudes and behavioural intentions to advocate deceased donor organ donation.
Lin LM, Lin CC, Chen CL, et al. Transplant Proc. 2014; 46(4):1036-40.