The May 2014 edition of the transplant trial watch is now available on the CET site, as well as our mobile apps for iPhone, iPad and Android. This month, studies include a systematic review of hypothermic machine preservation in renal transplantation, metallic stents for biliary strictures following liver transplantation and tablet computer-based patient education.
There has been very considerable enthusiasm for renal denervation for resistant hypertension in the last few years. However it is not a new idea and I well remember as a young surgeon in the late 60’s carrying out open renal denervation for hypertension under the direction of the renowned nephrologist, Professor Priscilla Kincaid-Smith. Anecdotally there […]
The Transplant Trial Watch for April 2014 is now available on the CET website and via our app for iPhone, iPad and Android. We have selected 10 RCTs reported in the past month and looked at their quality and impact. This month, trials include ATG vs IL2RAs in kidney transplantation, long-term outcomes from CNI withdrawal […]
The March 2014 edition of the Transplant Trial Watch is now available online and via the CET’s app for iPhone, iPad and Android. This month, trials include the effects of cyclosporin A and tacrolimus on fibrosis following liver transplantation for hepatitis C, intravesical vs. extravesical ureteroneocystostomy in renal transplantation and the use of sitagliptin in […]
An increased incidence of deep vein thrombosis in kidney transplant recipients was first reported from Oxford by Richard Allen in 1987.This is confirmed in a single centre study from Montreal over an 11 year period, where they used a nested case control study comparing patients with and without thromboembolism. Amongst 930 kidney transplant recipients there […]
Recently, the Centre for Evidence in Transplantation published an analysis of compliance with the CONSORT statement in reports of randomised controlled trials (RCTs) in transplantation, and found that the compliance left much to desire. A recent article in the Annals of Surgery analysed Consort compliance in 150 recently published RCTs in surgery, most of these being in […]
The February 2014 edition of the Transplant Trial Watch is now available on the CET website, and on our apps for iPhone, iPad and Android. This month, new trials include the use of octreotide in liver transplantation, B-cell induction therapy in high-risk kidney transplant recipients and conversion from tacrolimus to sirolimus in renal transplantation.
The January 2014 edition of the Transplant Trial Watch is now available. This month’s new trials include Letermovir for post-transplant CMV infection, a suggestion that Alemtuzumab increases de-novo DSA production and a phase I study of a novel TLR-2 monoclonal antibody. You can read the CET’s summaries of these trials (and more) on the CET […]
The December 2013 edition of the transplant trial watch is now available on the CET site, as well as via our app for iPhone, iPad and Android. This month trials include long-term follow-up of the BENEFIT study, hand assisted retroperitoneoscopic nephrectomy and steroid-free renal transplantation with Alemtuzumab induction.