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11th November 2013 / Last updated : 11th November 2013 Peter Morris Clinical trials

Intrarenal resistive index after renal transplantation

A recent paper in the New England Journal of Medicine from a group in the Netherlands led by the late Yves Vanrenterghem has reported a very careful investigation of the intrarenal Resistive Index in renal allografts using Doppler ultrasonography. The resistive index was measured at baseline and at regular intervals after transplantation at the time […]

11th November 2013 / Last updated : 11th November 2013 Peter Morris Clinical trials

Long-term follow up of tracheal transplant

Recently there was note of  a 5 year follow-up of the young woman, Claudia Castillio, who had a tissue engineered tracheal transplant in 2008. She has retained good lung function with no immunological complications and the only problem has been scarring around areas of the graft, particularly at the anastomoses which has required repeated endoluminal […]

1st November 2013 / Last updated : 1st November 2013 Simon Knight Clinical trials

November Transplant Trial Watch now Available

The November 2013 edition of the Transplant Trial Watch is now available on our website and via our apps for iOS and Android. This month, trials include CNI to mTOR conversion, low-pressure pneumoperitoneum for laparoscopic donors, and protocol biopsies in low-risk renal transplant recipients.

7th October 2013 / Last updated : 7th October 2013 Simon Knight Clinical trials

October Transplant Trial Watch now online

The October 2013 edition of the Transplant Trial Watch is now available on transplantevidence.com and via our app for iPhone, iPad and Android. This month, there are a number of interesting trials including failed attempts at inducing tolerance with donor stem cell infusions and an interesting protocol for a study looking at BK virus prophylaxis […]

2nd August 2013 / Last updated : 2nd August 2013 Simon Knight Clinical trials

August Transplant Trial Watch now online

The August 2013 edition of the Transplant Trial Watch is now available online, and via our iPhone, iPad and Android app. This month, trials include Mizoribine in renal transplantation, retroperitoneoscopic donor nephrectomy and biopsy reporting following lung transplant.

8th July 2013 / Last updated : 8th July 2013 Simon Knight Clinical trials

July Transplant Trial Watch now online!

The July 2013 Transplant Trial Watch is now online. The CET staff have selected and reviewed the quality of ten recent randomised controlled trials in the field of solid organ transplantation. Don’t forget, the trial watch is also available via our app for iPhone, iPad and Android, which has now been updated to support the […]

24th May 2013 / Last updated : 24th May 2013 John O'Callaghan Clinical trials

Multiple reviews of machine perfusion find reduced delayed function of kidneys but no effect on graft survival

A group from Sun Yat-sen University, Guangzhou, China has recently published a systematic review comparing the outcomes in patients receiving kidneys from donation after cardiac death (DCD). Deng et al conducted a meta-analysis using the results from four randomised controlled trials (351 kidneys).  Machine perfusion reduced the rate of delayed graft function compared to static […]

1st May 2013 / Last updated : 1st May 2013 Simon Knight Clinical trials

May 2012 Transplant Trial Watch now online

The May 2013 edition of the Transplant Trial watch is now available on the CET website and our Trial Watch app for iPhone, iPad and Android. This month, trials include long-term follow-up of steroid avoidance in liver transplantation, the eternal question of T-tubes following liver transplant and mizoribine in renal transplantation.

3rd April 2013 / Last updated : 3rd April 2013 Simon Knight Clinical trials

What trials in transplantation would you like to see?

Peter Morris gave the following presentation at this year’s British Transplant Society Congress after polling members as to what trials they would like to see performed in the field of transplantation in the near future. There are many interesting ideas to help guide future research projects. If you have any further ideas, please let us […]

2nd April 2013 / Last updated : 2nd April 2013 Simon Knight Clinical trials

Exclusion of elderly patients in clinical trials

There is an interesting editorial in this month’s Transplantation discussing the exclusion of elderly patients from clinical trials. Such practice clearly has an impact on the generalisability of the results of trials to an increasingly ageing transplant population (the proportion of US kidney transplant recipients aged 65 or over doubled from 7% to 16% between […]

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