News

May 2018 Transplant Trial Watch now available

By: Simon Knight | Posted on 2nd May 2018

The May 2018 edition of the Transplant Trial Watch is now available online. This month’s studies include the impact of allograft nephrectomy on subsequent transplants, the mid- and long-term risks of living kidney donation, and the use of transcatheter arterial embolisation in patients with APKD prior to transplant.

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March 2018 Transplant Trial Watch now available

By: Simon Knight | Posted on 2nd March 2018

The March 2018 Transplant Trial watch is now available online and via the CET app. This month’s papers include an evaluation of inclusion/exclusion criteria in transplant clinical trials, self-monitoring of kidney function after transplantation and extended versus modified right lobe grafts for live donor liver transplantation.

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February 2018 Transplant Trial Watch Now available

By: Simon Knight | Posted on 5th February 2018

The February 2018 Transplant Trial Watch is now available. This month’s articles include the results of the Borteject trial, results of the UK 3C study and a review of guidelines for cancer evaluation in solid organ transplant recipients.

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Do clinical trials reflect reality?

By: Simon Knight | Posted on 9th January 2018

Renal transplant recipients and donors are becoming increasingly more marginal, with more expanded criteria (ECD) and donation after circulatory death (DCD) donors and increasingly older recipients with multiple comorbidities. Despite this, high-risk donors and recipients are often excluded from clinical trials, leading to uncertainty about the generalizability of findings. In order to highlight the extent of this […]

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December 2017 Transplant Trial Watch now available

By: Simon Knight | Posted on 4th December 2017

The December 2017 edition of the Transplant Trial Watch is now available online. This month’s studies include PDT vs. Imiquimod for the treatment of actinic keratoses in transplant recipients, omitting affective attitude questions to improve intention to become an organ donor, and a meta-analysis of ECMO vs. bypass during lung transplantation.

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November 2017 Transplant Trial Watch now available

By: Simon Knight | Posted on 1st November 2017

The November 2017 Transplant Trial Watch is now available. This month’s papers include a non-inferiority study of low-dose sirolimus combined with tacrolimus in renal tranpslant recipients, a meta-anlysis of remote ischaemic conditioning protocols, and propofol to reduce hepatic ischaemia reperfusion injury.

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The PITHIA trial – a novel trial to improve kidney utilisation

By: Simon Knight | Posted on 4th October 2017

Soon to start recruiting in the UK, the Pre-Implantation Trial of Histopathology In renal Transplant Allografts (PITHIA) trial blends national collaboration, a unique digital pathology service, registry-based follow-up and a novel stepped-wedge design to assess the impact of a national donor histopathology service on kidney utilisation. The trial is being run by chief investigator Gavin […]

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October 2017 Transplant Trial Watch now available

By: Simon Knight | Posted on 4th October 2017

The October 2017 edition of the Transplant Trial Watch is now available. This month’s studies include long term results from the original phase II Belatacept study, a Cochrane review of monoclonal and polyclonal antibodies for renal transplant recipients, and a systematic review of in-situ perfusion techniques in liver transplantation.

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Do you work on Surgical Trials?

By: Simon Knight | Posted on 14th September 2017

Do you work in surgical trials? If so the PIRRIST team need your help! They are looking for surgical trial staff (in a variety of roles) to take part in an online questionnaire about their experiences of some barriers to successful recruitment, retention and PPI in UK adult surgical /surgery-related trials. They are offering a £10 […]

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July 2017 Transplant Trial Watch now online

By: Simon Knight | Posted on 5th July 2017

The July 2017 edition of the Transplant Trial Watch is now available. This month’s papers include a systematic review of factors affecting medication adherence following renal transplant, a trial of Belatacept versus tacrolimus in renal transplant recipients and a systematic review of transplant tourism.

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