CET wins government funding for a project exploring AI-driven decision support in organ offering
A project from the CET exploring the role of AI-drive decision support in kidney transplant offering has been awarded funding in the latest round of the Artificial Intelligence in Health and Care Award. The AI Award is making £140 million available to a number of projects over four years to accelerate the testing and evaluation […]
Read moreJanuary 2019 Transplant Trial Watch is now available
The first Transplant Trial watch of 2019 is now available online. This month, the TTW includes a trial of the use of coated ureteric stents, somatostatin as an inflow modulator in liver transplantation, and the use of naloxone in DBD lung donors.
Read moreMay 2018 Transplant Trial Watch now available
The May 2018 edition of the Transplant Trial Watch is now available online. This month’s studies include the impact of allograft nephrectomy on subsequent transplants, the mid- and long-term risks of living kidney donation, and the use of transcatheter arterial embolisation in patients with APKD prior to transplant.
Read moreMarch 2018 Transplant Trial Watch now available
The March 2018 Transplant Trial watch is now available online and via the CET app. This month’s papers include an evaluation of inclusion/exclusion criteria in transplant clinical trials, self-monitoring of kidney function after transplantation and extended versus modified right lobe grafts for live donor liver transplantation.
Read moreFebruary 2018 Transplant Trial Watch Now available
The February 2018 Transplant Trial Watch is now available. This month’s articles include the results of the Borteject trial, results of the UK 3C study and a review of guidelines for cancer evaluation in solid organ transplant recipients.
Read moreDo clinical trials reflect reality?
Renal transplant recipients and donors are becoming increasingly more marginal, with more expanded criteria (ECD) and donation after circulatory death (DCD) donors and increasingly older recipients with multiple comorbidities. Despite this, high-risk donors and recipients are often excluded from clinical trials, leading to uncertainty about the generalizability of findings. In order to highlight the extent of this […]
Read moreDecember 2017 Transplant Trial Watch now available
The December 2017 edition of the Transplant Trial Watch is now available online. This month’s studies include PDT vs. Imiquimod for the treatment of actinic keratoses in transplant recipients, omitting affective attitude questions to improve intention to become an organ donor, and a meta-analysis of ECMO vs. bypass during lung transplantation.
Read moreThe PITHIA trial – a novel trial to improve kidney utilisation
Soon to start recruiting in the UK, the Pre-Implantation Trial of Histopathology In renal Transplant Allografts (PITHIA) trial blends national collaboration, a unique digital pathology service, registry-based follow-up and a novel stepped-wedge design to assess the impact of a national donor histopathology service on kidney utilisation. The trial is being run by chief investigator Gavin […]
Read moreOctober 2017 Transplant Trial Watch now available
The October 2017 edition of the Transplant Trial Watch is now available. This month’s studies include long term results from the original phase II Belatacept study, a Cochrane review of monoclonal and polyclonal antibodies for renal transplant recipients, and a systematic review of in-situ perfusion techniques in liver transplantation.
Read moreSeptember 2017 Transplant Trial Watch now available
The September 2017 edition of the Transplant Trial Watch is now online. This month’s studies include paracalcitol in renal transplant recipients, a new formula for estimation of standard liver volume, and protective mechanical lung ventilation in lung transplantation.
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