News

Sirolimus use and cancer incidence in US kidney transplant recipients

By: Peter Morris | Posted on 10th February 2015

Recently we added to the Library as well as a blog  a very good individual patient meta-analysis of the use of sirolimus showing that it was associated with a reduction in cancer incidence but also with an increased rate of death after kidney transplantation.  Now we have a study of data from the US transplant registry […]

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Sirolimus and secondary skin cancer prevention in kidney transplantation

By: Peter Morris | Posted on 21st August 2012

Sylvie Euvrard and her colleagues (New England Journal of Medicine 2012; 367:329) have performed a multicentre randomised trial in patients on a calcineurin inhibitor who had developed at least 1 squamous cell cancer of the skin after renal transplantation. Patients were randomised to either continue on the calcineurin inhibitor or to be converted to sirolimus. […]

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