Researchers in Boston, Massachusetts have published the first description of successful transplantation of a bioengineered kidney into rats. The paper, published in this week’s Nature Medicine describes the process of decellularization by detergent perfusion and regeneration with epithelial and endothelial cells. The resulting kidney was capable of filtering and producing urine both in vitro and […]
The April 2013 edition of the Transplant Trial Watch is now available on the CET website. Each month, CET staff select 10 important RCTs in the field of transplantation, summarise the findings and assess trial quality. This month, trials include vildagliptin and pioglitazone for post-transplant glucose intolerance, sirolimus in transplant patients with squamous cell carcinoma […]
The February 2013 edition of the Transplant Trial Watch is now available on the CET website, and via our app for Android and iPhone. Each month the CET staff identify 10 new trials in the field of transplantation to summarise and assess the quality. This month, the trial watch includes trials of early versus late […]
Happy New Year to all of our readers! The January 2013 edition of the Transplant Trial is now available, with 10 recently published trials in the field of solid organ transplantation selected and appraised for quality. This month, there are results of pre-transplant antiviral therapy in liver transplantation, intensive insulin therapy in diabetic renal transplant […]
In this interesting analysis from the Collaborative Transplant Study the authors have analysed some 180,000 deceased donor kidney transplants performed between 1990 and 2009 and have found that the incidence of death with a functioning graft was 4.8% during the first year after transplant and 7.7% during years 2-5. The most frequent causes of death […]
The December 2012 edition of the Transplant Trial Watch is now available on the CET website. Each month, the CET staff select 10 important recent RCTs in the field of transplantation and summarise and appraise their quality. This month, trials include alternative procedures for living donor nephrectomy, Rapamycin in simultaneous kidney pancreas transplants and Everolimus […]
The October edition of the Transplant Trial Watch is now available on the CET website. Each month, our team summarise and assess the quality of 10 important randomised controlled trials in the field of solid organ transplantation. This month, trials include sirolimus in the prevention of skin cancer in transplant recipients, machine perfusion in extended […]
An analysis just produced by the Collaborative Transplant Study (CTS) (Newsletter 3; 2012) examined the most frequent cause of death in relation to HLA compatibility in the first 3 years after renal transplantation. The most frequent causes of death were infection (27%), cardiovascular disease (30%) and cancer (8%). It appeared that there were more deaths […]
The September edition of the Transplant Trial Watch is now available on the CET website. Each month, the CET staff select 10 recently published randomised controlled trials in the field of transplantation and summarise the findings and quality. This month, the Trial Watch includes a trial of generic tacrolimus, long-term results from the Tricontinental MMF […]
Philip Macklin was awarded an MSc in Surgical Sciences jointly from the University of Edinburgh and the Royal College of Surgeons in June of this year, with distinction. Working under the supervision of the CET, his dissertation was entitled “A Systematic Review of the Use of Rituximab in Renal Transplantation”. He is now preparing manuscripts […]