Tacrolimus maintenance doses
The Collaborative Transplant Study ( CTS ) first newsletter for 2014 (February 1 – available to CTS participants only) presents a particularly important analysis of outcomes of deceased donor kidneys between 2003 and 2012 based on the tacrolimus trough levels one year after transplantation. If the maintenance trough levels were less than 5ng/mL there was a significantly worse graft […]
Read moreHLA mismatch is associated with death with a functioning graft after kidney transplantation
In this interesting analysis from the Collaborative Transplant Study the authors have analysed some 180,000 deceased donor kidney transplants performed between 1990 and 2009 and have found that the incidence of death with a functioning graft was 4.8% during the first year after transplant and 7.7% during years 2-5. The most frequent causes of death […]
Read moreDonor and recipient age of kidney transplants is increasing
In the latest CTS newsletter (November 1 2012) there is a very interesting analysis of the age of both donors and recipients over the last 25 years. This shows that the age of donors is steadily increasing with 31% of donors being greater than 60 years of age and 27% between 50 and 59 years […]
Read moreMarked differences in kidney graft survival between Europe and the USA
This very interesting study is in publication in Transplantation. It is an analysis of deceased donor kidney graft survival in Europe and the USA based on CTS data and UNOS data comparing overall and age specific 1, 5 and 10 year graft survival for Europeans and white, African and Hispanic Americans over a 3 year […]
Read moreHLA matching and death with a functioning graft
An analysis just produced by the Collaborative Transplant Study (CTS) (Newsletter 3; 2012) examined the most frequent cause of death in relation to HLA compatibility in the first 3 years after renal transplantation. The most frequent causes of death were infection (27%), cardiovascular disease (30%) and cancer (8%). It appeared that there were more deaths […]
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