A recent article in the BMJ by Abraha et al, using large amounts of data from RCTs, has shown that deviation from intention-to-treat analysis (ITT) can lead to apparently larger treatment effects. When compared to standard intention-to-treat analysis there was a significant difference in the apparent treatment effect. When a deviation from ITT was compared […]
As you may be aware, the Centre for Evidence in Transplantation is co-ordinating the James Lind Alliance Priorities Setting Partnership in Renal Transplantation. The process aims to bring together pateints, carers and heathcare professionals to identify and prioritise areas for future research in kidney transplantation. The second steering group meeting was held at the Royal […]
A new national survey has opened, giving patients, their carers and the healthcare professionals looking after them an opportunity to submit questions about kidney transplantation and living donation that they think should be addressed in future research. The survey is open to all healthcare professionals caring for people who have had a kidney transplant, are […]
After a 1 month break for the World Transplant Congress, the September 2014 edition of the Transplant Trial Watch is now available on the CET website and via our mobile app. This month, studies include an interesting analysis of the relationship between uric acid levels and CAN from the ABCAN trial, de novo Belatacept in […]
The July 2014 edition of the Transplant Trial watch is now available on the CET website, and via our app for iPhone, iPad and Android. This month’s top ten trials include a systematic review of tuberculosis prophylaxis in renal transplantation, rituximab for desensitisation of cadaveric kidney recipients and the use of albuterol in DBD donors.
I went to an excellent lecture on PROs by Professor Melanie Calvert from the University of Birmingham as part of the Doll Seminar series today. She talked about the incorporation of PROs in randomised controlled trials but the quality of the reporting which was quite dismal. Many analyses that she and her group have done […]
The May 2014 edition of the transplant trial watch is now available on the CET site, as well as our mobile apps for iPhone, iPad and Android. This month, studies include a systematic review of hypothermic machine preservation in renal transplantation, metallic stents for biliary strictures following liver transplantation and tablet computer-based patient education.
The Transplant Trial Watch for April 2014 is now available on the CET website and via our app for iPhone, iPad and Android. We have selected 10 RCTs reported in the past month and looked at their quality and impact. This month, trials include ATG vs IL2RAs in kidney transplantation, long-term outcomes from CNI withdrawal […]